Molecular Biology Pharmaceuticals Protein Expression Protein Production 
Drug Discovery World
NOVEMBER 27, 2023
For instance, the engineering of CHO cells, widely used protein expression system, for various metabolic pathways has resulted in improved expression levels of large molecule drugs and product quality 1,2. After engineering, stable clones are screened, identified, and characterised. Biotechnol Bioeng 2012;118:2326.
Drug Target Review
MARCH 15, 2024
As discussed above, recent advances in gene editing tools and transposon-based vectors have facilitated targeted and consistent cell line engineering for the development of protein expressing CHO cell lines. Anis also serves on the scientific and editorial advisory board of Genetic Engineering News at Mary Ann Liebert, Inc.
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Drug Discovery World
APRIL 30, 2024
The biggest growth driver for mRNA therapeutics came from the Covid-19 pandemic, when mRNA-based vaccines proved effective in treating SARS-CoV-2, and pharmaceutical companies such as Pfizer/BioNTech and Moderna were successful in bringing these treatments to market. Wang YS, Kumari M, Chen GH, et al. J Biomed Sci 2023;30;84.
Drug Discovery World
NOVEMBER 9, 2023
Novel approaches This session will feature two luncheon presentations: Nicholas Field, Principal Scientist, Purification Development, Lonza, on: ‘Tailored CMC solutions to overcome the challenges in bispecific, Fab and Fc-fusion protein development programs’.
The Pharma Data
JANUARY 13, 2021
Germany-based Cevec Pharmaceuticals GmbH signed a licensing agreement with Biogen for the use of its proprietary ELEVECTA Technology for the manufacturing of adeno-associated virus (AAV) vectors for gene therapy applications. The deal will provide Biogen the rights to use the technology across their portfolio of gene therapy products.
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