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Driving efficiency across upstream bioprocess workflow

Drug Target Review

Transposons preferentially integrate the gene of interest into active transcriptional sites, facilitating rapid cell line development and higher titers of the protein drug. Furthermore, adoption of automated and standardised cell counting and clone selection technologies can help optimise cell line development workflows.

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Enhancing gene therapy with Circio

Drug Target Review

Secondly, circRNAs can be engineered for more efficient protein expression by carefully selecting and optimising the IRES element, a sequence motif derived from viruses and used to initiate cap-independent translation from circRNA. What improvements in protein expression and durability have been demonstrated by the circVec 2.1

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BioSpace Global Roundup: Cevec Licenses AAV Program to Biogen

The Pharma Data

Patients with severe COVID-19 infection often present with acute severe inflammation and organ failure. based Mogrify Limited expanded its research collaboration with MRC Laboratory of Molecular Biology. Recent studies conducted in the U.S. Mogrify – U.K.-based