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The mechanism of Semen Persicae?Flos Carthami in treating hypertrophic scar: A study based on network pharmacological analysis and in vitro experiments

Chemical Biology and Drug Design

However, the pharmacodynamic mechanism and molecular target of SP-FC in the treatment of HS are still unclear. Therefore, this study is intended to explore the mechanism and target of SP-FC in the treatment of HS through network pharmacology combined with in vitro cell and molecular biology experiments.

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Women in Stem with Dr Beate Mueller-Tiemann

Drug Target Review

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. I did my PhD project on elucidating the role of the p53 protein that is relevant in many cancers.

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Enhancing gene therapy with Circio

Drug Target Review

Secondly, circRNAs can be engineered for more efficient protein expression by carefully selecting and optimising the IRES element, a sequence motif derived from viruses and used to initiate cap-independent translation from circRNA. What improvements in protein expression and durability have been demonstrated by the circVec 2.1

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The future outlook for mRNA therapies

Drug Discovery World

The biggest growth driver for mRNA therapeutics came from the Covid-19 pandemic, when mRNA-based vaccines proved effective in treating SARS-CoV-2, and pharmaceutical companies such as Pfizer/BioNTech and Moderna were successful in bringing these treatments to market. The mice given the treatment survived for over three months.

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What to expect from PEGS Europe 2023: Day 2

Drug Discovery World

Sandra Ergueta-Carballo, PhD, Project Coordinator, University of Cambridge, on: ‘Advancing snake envenomation treatment: designing the next generation of antivenoms’. Jorge Dias, PhD, Principal Scientist, Alchemab Therapeutics, on: ‘A patient-first approach to discover first-in-class antibody therapeutics’.

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BioSpace Global Roundup: Cevec Licenses AAV Program to Biogen

The Pharma Data

Food and Drug Administration gave it the green light to initiate a Phase III study of tesamorelin for the treatment of adults with Nonalcoholic Steatohepatitis (NASH) with liver fibrosis. based Mogrify Limited expanded its research collaboration with MRC Laboratory of Molecular Biology. This week, the company said the U.S.