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Breakthrough technology leads to life-saving treatment for deadly skin reaction

Science Daily: Pharmacology News

Using innovative spatial proteomics -- one of the most advanced molecular biology tools -- the team identified the inflammatory JAK/STAT pathway as the main driver of disease. A global team of researchers has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis.

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Organoids: the versatile platform for discovery and regeneration

Drug Target Review

8 With the widespread use of induced pluripotent stem cells (iPSCs), organoids can now be generated from the skin or blood cells of both healthy volunteers and disease patients, opening the door to studying various diseases and creating individually customised potential treatments. Organoids in cancer research. Nat Rev Cancer. Cell Stem Cell.

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Logistics in Focus: Orchestrating the Challenges of Cell Therapy

Conversations in Drug Development Trends

These advanced therapeutics harness the power of molecular biology to improve human health. Cell therapy can be effective, but clinically testing the treatment presents several logistical challenges that require early planning and rigorous management by specialized and experienced teams throughout the clinical trial timeline.

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The mechanism of Semen Persicae?Flos Carthami in treating hypertrophic scar: A study based on network pharmacological analysis and in vitro experiments

Chemical Biology and Drug Design

However, the pharmacodynamic mechanism and molecular target of SP-FC in the treatment of HS are still unclear. Therefore, this study is intended to explore the mechanism and target of SP-FC in the treatment of HS through network pharmacology combined with in vitro cell and molecular biology experiments.

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Nucleic acid therapy accelerator

Drug Target Review

elegans applicable to larger brains, including those of fish, octopuses, mice, and humans, and if so, what implications does this have for neuroscience and potential treatments for neurological conditions? He is also a Professor of Biology at the University of Leuven, a member of EMBO and a Fellow of the Academy of Medical Sciences.

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Advancing CAR-T therapy: how CD5 modulation is shaping cancer treatment

Drug Target Review

However, these treatments will eventually fail for the majority of patients, so there is a strong need for better CAR therapies. How might the CD5 knockout approach impact the treatment of other types of cancers beyond T-cell lymphoma?

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Women in Stem with Dr Beate Mueller-Tiemann

Drug Target Review

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. Can you tell us about your journey in the field of STEM and the challenges you encountered along the way?