Drug Target Review

JULY 4, 2023

1 Regulators invest significant consideration balancing quality-of-life measures with overall survival when assessing novel oncology treatments. Driving towards lower dosing and better targeting to address safety concerns and enhance efficacy is a common goal that unites the global oncology research and development community.

Small Molecule 145

Small Molecule Drugs Clinical Pharmacology Trials 145

Agency IQ

SEPTEMBER 15, 2023

PFAS regulation in California (late 2023 edition) California consistently maintains its status as both one of the most important economies in the world as well as one of the most regulated states in the United States. In 2019, the state began to significantly ramp up its PFAS regulation and research.

Regulations 40

Regulations Packaging Production Organic Chemistry 40

Agency IQ

AUGUST 25, 2023

This bond is one of the strongest in organic chemistry, making this family of chemicals highly effective at resisting water, oil, and heat. PFAS regulation in the E.U. Two high-profile initiatives to regulate PFAS in the E.U. are currently underway.

Regulations 40

Regulations Government Packaging Organic Chemistry 40

Drug Hunter

AUGUST 21, 2023

The BBB is composed of specialized brain endothelial cells that regulate the distribution of molecules into and out of the brain from the blood. Unlike the endothelial BBB, the blood-cerebrospinal fluid-barrier (BCSFB) is made up of epithelial cells that similarly regulate the distribution of molecules between the blood and CSF.

Drugs 206

Drugs Disease Targeted Protein Degradation Screening Hits 206

Broad Institute

NOVEMBER 17, 2023

Alicia Martin (MGH) genetics, diversity, evolution, ancestry, large-scale, population genetics, neuropsychiatric, heritable, data, analysis psychatric disorders statistical methods, community resources for genomics, and research capacity for multi-ancestry studies Genetics Studies the heritable basis of psychiatric disorders in diverse populations.

Engineering 52

Engineering Organic Chemistry Molecular Biology Disease 52

Agency IQ

JULY 7, 2023

These carbon-fluorine bonds are some of the strongest in organic chemistry, meaning that most PFAS readily persist in the environment. Under the framework, new PFAS are expected to be considered persistent, bioaccumulative, and toxic (PBT) chemicals, which invokes another level of regulation for these future PFAS.

Laboratories 40

Laboratories Regulations Organic Chemistry Research Laboratories 40

Drug Target Review

DECEMBER 22, 2023

My secondary school chemistry teacher had a PhD in organic chemistry, and I found her classes and lab experiments to be very interesting, especially those in physical and organic chemistry. Could you share an example of a specific project or research that you have worked on and the impact it has had in your field?

Organic Chemistry 105

Organic Chemistry Science Pharmaceuticals Pharmacy 105