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Women in STEM with Dr Catherine Sheehan

Drug Target Review

My secondary school chemistry teacher had a PhD in organic chemistry, and I found her classes and lab experiments to be very interesting, especially those in physical and organic chemistry. Could you share an example of a specific project or research that you have worked on and the impact it has had in your field?

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Bavtavirine

New Drug Approvals

Institute of Organic Chemistry and Biochemistry of the AS CR, v.v.i. Bavtavirine can be used for HIV disease research. Benzonitrile, 4-[[4-amino-8-[4-[(1 E )-2-cyanoethenyl]-2,6-dimethylphenyl]-2-quinazolinyl]amino]- Gilead Sciences, Inc.; Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitors (NNRTIs).

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Women in Stem with Dr Emily Leproust

Drug Target Review

I started my journey in chemistry – first as an undergraduate and then in my PhD programme at the University of Houston, where I focused on organic chemistry and nucleic acids chemistry. Could you share an example of a specific project or research that you have worked on and the impact it has had in your field?

DNA 116
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Chemotherapy-free treatment for patients with blood cancer

Drug Target Review

In this article, Dr Andy Souers, distinguished research fellow at AbbVie in Oncology Discovery Research, discusses a 20-year quest for AbbVie researchers to find an enhanced therapeutic chemotherapy-free approach for blood cancer, that restores the body’s ability to fight cancer.

Treatment 105
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Antibody Drug Conjugates: windows of opportunity

Drug Target Review

Patient advocacy groups, such as Friends of Cancer Research, are also encouraging regulators to ensure drug developers in the oncology space invest in the optimisation of dosing regimens to help better balance efficacy and safety and thereby deliver more effective patient outcomes. Antibody drug conjugated with cytotoxic payload.

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Why Cats Sniff Each Other’s Butts

PLOS: DNA Science

Now a research team from the Department of Evolution and Ecology and Genome Center University of California, Davis, explains why, with their cataloging of the microbiomes of domestic cat anal glands. The bacterial members of the microbiome produce and release organic compounds that affect the behavior of another cat.

DNA 97
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Welcome to new Director David Hulcoop

The Open Targets Blog

After completing my PhD in organic chemistry at the University of Cambridge, I went to Canada as a Leverhulme Trust postdoctoral fellow. Much of our work at Open Targets is about trying to enhance the translational impact of scientific research happening on the Wellcome Genome Campus , near Cambridge, UK.