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New chemical process makes it easier to craft amino acids that don't exist in nature

Science Daily: Pharmacology News

Chemists describe a powerful new way to create new-to-nature, 'unnatural' amino acids, which could find use in protein-based therapies and open up novel branches of organic chemistry.

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Women in STEM with Dr Catherine Sheehan

Drug Target Review

My journey and interest in STEM began initially because of my secondary school Biology and Chemistry teachers. Both were woman teachers who were passionate about science and very good teachers to boot. As a result, I was very well prepared when I entered university to study science.

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API Processes in the Pharmaceutical Industry

DS in Pharmatics

I earned a Bachelor of Science in Chemistry at Fairfield University in 1979 and a Ph.D. in Organic Chemistry at Yale University in 1984 […] James Mencel’s Guidanceabout Scaling Up API Processes. Could you please introduce yourself and your expertise in the pharmaceutical industry?

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Bavtavirine

New Drug Approvals

Benzonitrile, 4-[[4-amino-8-[4-[(1 E )-2-cyanoethenyl]-2,6-dimethylphenyl]-2-quinazolinyl]amino]- Gilead Sciences, Inc.; Institute of Organic Chemistry and Biochemistry of the AS CR, v.v.i. Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitors (NNRTIs).

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Women in Stem with Dr Emily Leproust

Drug Target Review

I started my journey in chemistry – first as an undergraduate and then in my PhD programme at the University of Houston, where I focused on organic chemistry and nucleic acids chemistry. They had the science and the technology but not the business model. Twist was officially founded in 2013.

DNA 116
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Michael Crichton and James Patterson’s “Eruption” is Riveting, but with a Shaky Genetic Foundation

PLOS: DNA Science

Not Just a Volcanic Eruption – Sinister Science, Too Spoiler alert! My knowledge of the field is only what I learned in high school earth science and watching Heather barf on the volcano, but I assume his comments are accurate. The tale opens at the Hilo Botanical Gardens in 2016. Then, nobody checked scientific plausibility.

DNA 70
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Welcome to new Director David Hulcoop

The Open Targets Blog

After completing my PhD in organic chemistry at the University of Cambridge, I went to Canada as a Leverhulme Trust postdoctoral fellow. I knew I wanted to stay close to science, but I wanted a new adventure. The Open Targets role was in a different area of science, at the other end of the drug discovery process.