Drug Target Review

JULY 4, 2023

These therapies have broadened treatment options for patients to expand beyond the more traditional small molecule drug alternatives. Patients and caregivers also assess the benefits offered by different therapies, weighing the progression-free survival with their off-target effects. 3D rendering of Antibody Drug Conjugate Molecules.

Small Molecule 145

Small Molecule Drugs Clinical Pharmacology Trials 145

Drug Target Review

MAY 1, 2024

T-DM1, for example, is approved in patients with HER2-positive breast cancer and residual invasive cancer following neoadjuvant therapy. At Zymeworks we apply a holistic approach to optimise each of the ADC components, leveraging insights gained from clinical trials and real-world clinical experience to inform the design of novel ADCs.

Drugs 69

Drugs FDA Approval Organic Chemistry Small Molecule 69

The Open Targets Blog

SEPTEMBER 21, 2023

After completing my PhD in organic chemistry at the University of Cambridge, I went to Canada as a Leverhulme Trust postdoctoral fellow. These very large teams need to stay on track to hit delivery milestones for clinical trials. Photo credit: Jeff Dowling, EMBL-EBI What is your professional background?

Organic Chemistry 82

Organic Chemistry Process Chemistry Small Molecule Science 82

The Pharma Data

OCTOBER 23, 2020

A graduate of the Hebrew University of Jerusalem, he earned a Bachelor of Science in chemistry and physics and a Master of Science in physical organic chemistry before completing a Doctor of Philosophy in 1971. and Pure Tech Health. He also remains active as the chief executive officer and chairperson of AZTherapies Inc.

Organic Chemistry 52

Organic Chemistry Clinical Trials Science Pharmaceuticals 52

Drug Target Review

MAY 31, 2024

Coupling my desire to be a scientist with my keen sense of adventure, I moved to Alaska out of high school to begin my undergraduate studies in chemistry, applying myself to my STEM classes whilst also climbing mountains and chasing Northern Lights.

Organic Chemistry 45

Organic Chemistry Computational Chemistry Small Molecule Disease 45

PLOS: DNA Science

APRIL 17, 2025

Adding these two conditions, experts say, would identify 400 to 450 babies a year whose lives could be saved, with gene therapy. That’s the case for some gene therapies. She was integral in pursuing the gene therapy for other families, even though Calliope Joy couldn’t benefit from it. (See

Therapies 96

Therapies Bioethics DNA Organic Chemistry 96