Drug Target Review
JULY 4, 2023
These therapies have broadened treatment options for patients to expand beyond the more traditional small molecule drug alternatives. ADCs have the potential to redress the poor balance between safety and efficacy seen with traditional cancer treatment options.
New Drug Approvals
MARCH 26, 2025
Institute of Organic Chemistry and Biochemistry of the AS CR, v.v.i. Bavtavirine is part of highly active antitiretroviral therapy (HAART) treatment regimen. Benzonitrile, 4-[[4-amino-8-[4-[(1 E )-2-cyanoethenyl]-2,6-dimethylphenyl]-2-quinazolinyl]amino]- Gilead Sciences, Inc.; Bavtavirine can be used for HIV disease research.
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Drug Target Review
MAY 1, 2024
How have advancements in antibody-drug conjugates (ADCs) expanded treatment options for different types of cancer? For example, enfortumab vedotin in combination with anti-PD-1 pembrolizumab reshaped the first-line treatment of patients with previously untreated metastatic urothelial cancer, doubling OS compared to standard of care.
The Open Targets Blog
SEPTEMBER 21, 2023
After completing my PhD in organic chemistry at the University of Cambridge, I went to Canada as a Leverhulme Trust postdoctoral fellow. For example, there are often many potential targets you could consider developing a treatment against for a given disease; how do you choose between them? I’m a chemist by training.
The Pharma Data
NOVEMBER 11, 2020
McChesney is the founder and chief executive officer of Cloaked Therapeutics and Arbor Therapeutics, through which he has drawn on more than five decades of research in natural products chemistry to identify and develop novel cancer treatments.
The Pharma Data
OCTOBER 23, 2020
A graduate of the Hebrew University of Jerusalem, he earned a Bachelor of Science in chemistry and physics and a Master of Science in physical organic chemistry before completing a Doctor of Philosophy in 1971. Dr. Elmaleh has contributed to more than 130 book chapters, scientific papers, and professional journal articles.
Drug Target Review
MAY 31, 2024
Coupling my desire to be a scientist with my keen sense of adventure, I moved to Alaska out of high school to begin my undergraduate studies in chemistry, applying myself to my STEM classes whilst also climbing mountains and chasing Northern Lights.
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