Antidote

JULY 27, 2023

Before any new therapy can be put on the market, it must be tested to ensure its safety and effectiveness, and the research for this process is done through clinical trials.

Clinical Research 98

Clinical Research Research Clinical Trials Packaging 98

PPD

NOVEMBER 11, 2024

As companies undertake these steps, they increasingly rely on supply partners like Thermo Fisher who can address challenges in real time, helping maintain the highest levels of quality throughout the process without losing time or momentum.

Drug Development 97

Drug Development Clinical Trials Drugs Small Molecule 97

Advarra

JULY 5, 2022

Individuals invest a great deal to participate in clinical research, undertaking risks and burdens, while giving of their time and energies to advance scientific knowledge and the public good. Aggregate and Individual Research Results. Reasons Supporting Return of Individual Research Results.

Research 97

Research FDA Approval FDA Packaging 97

Broad Institute

JULY 19, 2023

Researchers reprogram gene therapy viral vectors to bind specific protein targets By Allessandra DiCorato July 19, 2023 Breadcrumb Home Researchers reprogram gene therapy viral vectors to bind specific protein targets A new screening method zeroes in on adeno-associated viruses that enter the brain through a defined mechanism.

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Therapies Research Engineering Virus 98

PPD

JULY 20, 2023

In clinical research, the role of drug packaging systems cannot be overlooked. Industry guidelines require biopharmaceutical and biotechnology companies to test their pharmaceutical packaging systems, as the systems often experience prolonged and intimate contact with drug products, drug substances and intermediates.

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Packaging Laboratories Pharmaceutical Companies Compliance 52

SCIENMAG: Medicine & Health

JUNE 22, 2023

A new study led by researchers from the Mass General Brigham healthcare system suggests that taking a “food is medicine” approach could increase nutrition security for families and lead to reductions in body mass index (BMI) in children.

Packaging 70

Packaging Research 70

SCIENMAG: Medicine & Health

JULY 17, 2023

Indiscriminate use of packaging materials derived from petroleum has led to a huge buildup of plastic in landfills and the ocean, as these materials have low degradability and are not significantly recycled.

Packaging 87

Packaging Research Production 87

Broad Institute

AUGUST 7, 2024

Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy By Allessandra DiCorato August 7, 2024 Breadcrumb Home Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy The method could accelerate the development of more effective adeno-associated viruses (AAVs).

Therapies 84

Therapies Research Engineering Packaging 84

Broad Institute

FEBRUARY 21, 2024

Today, Khalid is a single-cell computational analysis specialist in the lab of Steve McCarroll within the Broad’s Stanley Center for Psychiatric Research. I’ll say I’m excited about interactive visualizations, which are built on top of open source plotting packages such as R.

Engineering 116

Engineering Research Science Bioinformatics 116

SCIENMAG: Medicine & Health

JULY 21, 2023

Katy Börner’s team from the Luddy School of Informatics, Computing, and Engineering’s Cyberinfrastructure for Network Science Center has made significant contributions to constructing a Human Reference Atlas and has led or co-authored six research articles in a just-released HuBMAP package in Nature. Börner, Victor H.

Research 66

Research Packaging Engineering Science 66

The Open Targets Blog

JANUARY 30, 2025

gget ( [link] ) is a free, open-source command-line tool and Python package designed to enable efficient querying of large genomic databases, such as Ensembl, UniProt, and NCBI. The gget opentargets module plays a key role in enabling researchers to interpret the identified variants. What is gget?

Bioinformatics 76

Bioinformatics Immune Response RNA Packaging 76

Drug Target Review

JUNE 9, 2023

This exclusive interview with Dr Sharon Benzeno, Chief Commercial Officer, Immune Medicine at Adaptive Biotechnologies, unveils some ground-breaking research on T- cell therapy for cancer , which has seen the first TCR-based therapeutic candidate progress to clinical development, offering promising advancements in innovative cancer treatments.

Treatment 106

Treatment Packaging Clinical Research Therapies 106

SCIENMAG: Medicine & Health

SEPTEMBER 1, 2023

We are constantly exposed to phthalates in our environment through plastic products such as storage containers, medical devices, packages, fabrics, and toys. In a new study, researchers used mice […] Specifically, di-isononyl phthalate is inevitably becoming a part of our lives.

Packaging 87

Packaging Production Research 87

Broad Institute

JULY 10, 2024

Now, researchers at the Broad Institute of MIT and Harvard and the University of Iowa have developed a gene-editing approach that efficiently corrects the most common mutation that causes cystic fibrosis, found in 85 percent of patients. The new approach also generated 3.5

Engineering 145

Engineering Packaging DNA Treatment 145

PPD

MARCH 11, 2025

While individual rare diseases affect populations that are small in numbers, collectively they impact millions globally, posing significant health and research challenges. This solution allows researchers to enhance the robustness of their control populations, minimize bias and provide a real-world context to trial outcomes.

Drug Development 52

Drug Development Clinical Trials Disease Trials 52

Broad Institute

MAY 16, 2024

But FDA-approved forms of the most commonly used vehicle for packaging and delivering these therapies to target cells, adeno-associated viruses (AAVs), aren’t able to efficiently cross the blood-brain barrier at high levels and deliver therapeutic cargo. Several of these therapies have shown evidence of reaching the brain in humans.

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Therapies FDA Approval Engineering Disease 137

SCIENMAG: Medicine & Health

JULY 27, 2023

Supported by the EU-call Circular Bio-based Europe Joint Undertaking (CBE JU), the research project establishes a value chain for sustainable products such as textiles, food packaging and reinforced composites ready for the consumer […]

Packaging 74

Packaging Production Research 74

Broad Institute

DECEMBER 13, 2023

By Leah Eisenstadt December 13, 2023 Two teams of Broad researchers produced detailed maps of the mouse nervous system. Related news Researchers map brain cell changes in Alzheimer’s disease Courtesy of the Chen and Macosko labs. Courtesy of the Chen and Macosko labs. Our results underscore the need to study them more deeply.”

DNA 140

DNA Virus Research Engineering 140

The Pharma Data

MAY 17, 2021

In a separate Research Letter, Simon J. Gunter, MPhil, and his colleagues at the PORTAL research group provides an analysis of the effect of market exclusivity of drugs under FDA’s Unapproved Drug Initiative (UDI).

Research 52

Research FDA Approval Drugs FDA 52

Agency IQ

JANUARY 19, 2024

Commission unveils “one substance, one assessment” reform package The Commission has long aspired to realize its one substance, one assessment concept in the EU’s chemical regulatory regime. This provision is intended to prevent the duplication of studies among industry and keep the authorities abreast of what safety research is ongoing.

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Packaging Regulations Laboratories Animal Testing 40

DrugBank

JULY 20, 2023

Since each disease is present in small groups of patients, this research is also fraught with complex challenges. Limited numbers of patients translate to scarce information, making this research risky and expensive. This new resource for rare disease research will be integral to our overall drug development solution.

Disease 98

Disease Clinical Trials Trials FDA 98

KIF1A

OCTOBER 21, 2023

Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. To transport each piece individually would be very inefficient, so molecules going to the same destination are often packaged into containers we call vesicles.

Regulations 105

Regulations Doctors Disease Packaging 105

Fierce BioTech

DECEMBER 12, 2023

Is your organization harnessing the full potential of preclinical metadata for analyses, internal decision making, and to support R&D packages? Is your organization harnessing the full potential of preclinical metadata for analyses, internal decision making, and to support R&D packages? Learn how with this must-have guide.

Packaging 52

Packaging International Drugs Research 52

The Open Targets Blog

OCTOBER 24, 2023

  Together with Ray Kamalika, a research bioinformatician at OMass Therapeutics, he developed Otargen , an R package offering a suite of functions to facilitate the retrieval and analysis of Open Targets Genetics data, including specialised plotting functions to help visualise the information.   Have you used Otargen?

Bioinformatics 62

Bioinformatics Packaging Pharmaceutical Companies Pharma Companies 62

Olympian Clinical Research

JUNE 27, 2023

Typically, it’s wise to avoid: Dairy products and their alternatives (cow’s milk, cheese, butter) Gluten-containing grains (wheat, barley, rye) High-sugar foods and refined carbohydrates (sugary treats, sodas, processed snacks) Processed and packaged foods with additives, preservatives, and artificial ingredients.

Clinical Research 52

Clinical Research Packaging Doctors Production 52

DrugBank

SEPTEMBER 12, 2024

At DrugBank we’re committed to improving your daily research and drug development operations. It’s designed to fit naturally into your existing processes, enhancing your ability to collaborate with standardized definitions and focus on your research tasks.

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Production Government Packaging Research 98

The Pharma Data

NOVEMBER 18, 2021

Gilead’s option, on a program-by- program base, expires after a specified period of time following the achievement of a development corner for similar program and Arcus’s delivery to Gilead of the needful qualifying data package.

Research 52

Research Clinical Development Small Molecule Packaging 52

Quanticate

AUGUST 27, 2021

Even though R as a programming language is constantly growing in popularity in the pharmaceutical industry, it is still quite unpopular to use R in the preliminary stages of research like importing data from different sources, tidying it, calculating new variables in datasets and making other amendments available in SAS data steps.

Packaging 52

Packaging Pharmaceuticals Research 52

Practical Cheminformatics

JANUARY 8, 2024

Aside from some very brief demos on code generation and literature searches, mentions of LLM applications in preclinical research were scarce. A preprint from Microsoft AI Research provided a broad catalog of potential LLM applications in the physical and life sciences. Most of the drug discovery examples were underwhelming.

Drugs 136

Drugs Small Molecule Bioinformatics Packaging 136

The Pharma Data

AUGUST 7, 2020

CluePoints provides clinical studies with risk management support package during Covid-19. Patrick Hughes, Co-Founder and Chief Commercial Officer of CluePoints, said: “The response to our complimentary risk assessment package has been fantastic.

Clinical Trials 52

Clinical Trials Trials Packaging Therapies 52

FDA Law Blog: Biosimilars

MARCH 3, 2024

Biotechnology equipment includes genetic sequencers, mass spectrometers, polymerase chain reaction machines or any other equipment, components or accessories designed for the research, development, product, or analysis of biological materials as well as any software, firmware, or other digital components.

Small Molecule 102

Small Molecule Government FDA Approval Regulations 102

Drug Target Review

AUGUST 7, 2024

Packaging is typically the patient’s first interaction with a product, and it is critical for communicating safety and benefit-risk information. High quality artwork ensures that the product packaging conveys reliability and professionalism to foster trust within the product.

Drug Development 59

Drug Development Clinical Pharmacology Clinical Trials Drugs 59

Advarra

DECEMBER 12, 2023

The clinical research industry, like many others, has continued to be challenged by staff turnover in recent years. Clinical research organizations everywhere are seeing an influx of employees leaving their positions to go elsewhere. Understanding this issue is essential to a healthy research organization.

Clinical Research 52

Clinical Research Clinical Trials Packaging Trials 52

Drug Target Review

AUGUST 6, 2024

The availability of well-characterised targets is essential and oncology benefits from extensive research identifying tumour-specific antigens, making it a fertile ground for ADC development. Portfolio diversification is another strategy, with companies investing in multiple therapeutic areas to balance risk and maximise opportunities.

Therapies 120

Therapies Pharmaceutical Companies Disease Treatment 120

Advarra

JULY 19, 2022

If you mean using a different contract research organization (CRO) for the different phases of clinical trials – that’s different. Q: What is the typical time period between the submission of the briefing package and the pre-IND meeting? Q: The speaker just stated that the Meeting Package is due 60 days before the meeting date.

Packaging 52

Packaging FDA Trials Regulations 52

PPD

MARCH 13, 2024

In addition, oversight of the detailed tracking and traceability via GPS-enabled technology and monitoring the temperature and essential packaging requirements is a critical communication link between the CLM and the assigned courier.

Clinical Development 98

Clinical Development Clinical Trials Therapies Trials 98

Broad Institute

SEPTEMBER 13, 2023

Developing diagnostics and treatments By Rose Circeo September 13, 2023 Breadcrumb Home Developing diagnostics and treatments At the Broad Institute, researchers are revealing deep biological insights about the causes of disease, which are leading to new ways to monitor, diagnose, and treat patients with greater precision.

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Therapies Engineering Virus Packaging 52