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Re-Imagining Med Chem Strategies: the Tyranny of the n+1 Compound

DrugBaron

Finding small molecule drugs is much harder than finding a needle in a haystack – discovering the right arrangement of atoms to bind precisely to a protein target to elicit a particular response is a problem of vast dimensionality. Yet the situation with small molecules is even worse.

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Roche acquires Irish biotech firm Inflazome

The Pharma Data

Swiss pharma company to acquire biotech for $449m (€380m). Swiss pharma company Roche is set to acquire Irish biotech firm Inflazome for an upfront payment of $449m (€380m). Activated NLRP3 is involved in the production of pro-inflammatory cytokines IL-1?

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Women in Stem with Lidia Pieri

Drug Target Review

Sibylla’s scientific founders come from very different scientific fields that do not usually speak to each other, such as theoretical physics, molecular biology and pharmaceutical chemistry. We also have collaborations with pharmaceutical companies where we leverage the best of our unique platform and pharma expertise on the target.

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Algae: a source for prebiotics and drugs to treat IBD

Drug Target Review

Algae – an overlooked resource for new therapies It is only in recent years that algae research has expanded beyond their potential for producing biodiesel, to also consider them as a bio-resource, not only for novel prebiotics but also for compounds with unique structures and pharmaceutically relevant bioactivities.

Drugs 75
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BioSpace Movers & Shakers, Dec. 18

The Pharma Data

Hartfield previously served as CEO of Vitae Pharmaceuticals prior to its acquisition by Allergan. X4 Pharmaceuticals – Diego Cadavid was named chief medical officer of Boston-based X4 Pharmaceuticals. Cadavid will be responsible for the strategy, direction and execution of the company’s clinical development programs.

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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

There, I supported AI-enabled DD efforts in their small molecule portfolio. big pharma or startups/spin off? thanks Big pharma experienced is very well respected within biotech or small-startups. Where do you enjoy more to work? What pro/cons?

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First in Human Episode #54 featuring Ahmed Hamdy

Vial

Explore the groundbreaking VersAptx bioconjugation platform, designed to elevate cancer therapies and uncover the delicate balance between clinical excellence and commercial viability in the dynamic landscape of pharmaceuticals. We can link small molecule drugs to a payload that would enter in the cell and kill it.