Drug Discovery World

AUGUST 22, 2023

Originator pharma companies are developing ever more complex products, which are transforming the medical landscape, but their cost places an increasing burden on healthcare budgets worldwide. Opportunities Originator pharma companies are developing more and more complex products these days.

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PPD

JULY 13, 2023

Site and patient recruitment vendors are vital in supporting clinical trial operations across all phases and therapeutic areas. Their services help engage a suitable participant pool, facilitate clinical trial participation, ensure that selected sites have the resources to support clinical trial activities and more.

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Drug Discovery World

JANUARY 24, 2023

Virtual clinical trials ‘Virtual’ and ‘technology’ are concepts which are readily exchanged in this industry, but these are more than just buzzwords. The overall virtual clinical trials market is currently valued at $7.8 In early November 2022, two Alzheimer’s drugs were tested head-to-head in a first-ever virtual clinical trial 3.

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Drug Discovery World

MARCH 29, 2023

Moreover, an extra six months of RDP for drugs with full comparator clinical trials (rather than showing only that a drug is no worse than the standard of care). Will this be a viable solution? Clinical trials The draft outlines the requirement for clinical trials in children where a drug is approved in adults for a different disease.

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Drug Discovery World

OCTOBER 16, 2023

The campus is home to GSK, the Cell and Gene Therapy Manufacturing Catapult, LifeArc and Cytiva, alongside a growing cluster of start-up companies which together have raised £2.9 Next, Saleko highligts how Northumberland and the North East of the UK are recognised for pharmaceutical manufacturing prowess. billion in funding.

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Drug Discovery World

JULY 18, 2022

Troy Groetken of intellectual property and technology law firm McAndrews, Held & Malloy tells Lu Rahman how pharma companies can take this data from where it currently stands (drug design and development) to a more clinical level. Groetken sees many opportunities to utilise big data and AI in pharma.

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Drug Target Review

MARCH 15, 2024

Cultural differences between the UK and mainland Europe were still quite different then but we settled in Southampton and I later went to University in Brighton, studied for a D.Phil, and found a job at a Pharma company. How important is it to have role models for young women working in the pharmaceutical industry?

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Drug Discovery World

JULY 2, 2024

So, in this way there is a cross fertilisation from the bigger companies to newer ones. Start-ups will also take drug candidates from the pharma companies that are not getting attention for one reason or another and develop those into viable commercial products.”

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Vial

MARCH 1, 2024

Introduction Contract research organizations (CROs) are essential in pharmaceutical research and development (R&D). Throughout its journey, PPD has been committed to consistent quality and execution, customer-aligned service, and continuous innovation to accelerate clinical trial execution. Thermo Fisher Scientific Inc.’s

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Drug Discovery World

APRIL 20, 2023

Regulators are therefore used to seeing cognitive data as primary or secondary outcomes in clinical trials, and are familiar with the instruments and methodological nuances of such data. Is it time for the pharmaceutical industry to join in? We believe so.

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The Pharma Data

DECEMBER 21, 2020

The trial will be conducted at 10 sites across Germany and led by principal investigator Prof. The FOCUS trial is Ultimovacs’ fourth Phase II clinical trial with UV1 and comes in addition to the collaboration Phase II trial announced in May 2020. “We Mascha Binder, M.D.,

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Drug Discovery World

NOVEMBER 16, 2022

Here, DDW’s Reece Armstrong speaks to Dan O’Connor, VP of drug discovery at Molecular Devices, about what the OIC offers to pharmaceutical companies and the advantages and barriers of 3D biology. . 2D biology has been used by pharmaceutical researchers for decades. 2D vs 3D . The benefits to drug development are obvious then.

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Drug Discovery World

FEBRUARY 10, 2023

Scandinavia represents one of the most exciting but perhaps underrepresented markets for the discovery and development of pharmaceuticals. Sweden remains Scandinavia’s powerhouse market for pharmaceutical research and development. Sweden remains Scandinavia’s powerhouse market for pharmaceutical research and development.

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The Pharma Data

DECEMBER 23, 2020

Eligible patients enrolled in the trial receive treatment with AIM’s flagship pipeline drug Ampligen. The Ampligen EAP protocol is authorized to enroll up to 100 active trial participants, 20 of whom may be Long Haulers. development pipeline for ME/CFS. All study subjects will receive the same Ampligen treatments. See: PLOS ONE ).

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Predictive Oncology

FEBRUARY 7, 2023

“We’re providing that richness of tumor diversity and the population diversity that normally the companies will not be able to see until they are in a clinical trial and [the drug is] challenged against a multitude of different patients.”

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The Pharma Data

SEPTEMBER 14, 2020

Supply chain uncertainty is a challenge every clinical supply chain manager wrestles with – stemming from increasing product demand and quality, the growing complexity of clinical trial designs and a lack of visibility in the supply chain. Accelerating your clinical trial supply through digitalization.

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Drug Discovery World

OCTOBER 4, 2022

The pandemic might have affected the number of clinical trials taking place for cell and gene therapies, with activity decreasing by around 15% compared to 2020, but major therapies such as Novartis’ gene therapy drug for spinal muscular atrophy (SMA) Zolgensma still made it to market. . billion, compared to $19.9 Automation.

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The Pharma Data

JANUARY 17, 2021

This week another biopharma announced the disappointing news that their trial too had failed to make an impact on the devastating progression of Alzheimer’s. Nonetheless, the company plans to advance the drug to a full Phase III program with a larger sample size and a higher-dose arm. . Glutamate dysfunction is a feature of AD.

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The Pharma Data

DECEMBER 11, 2020

The University of Oxford has regularly appeared in our updates since July 2020, as its team of researchers leads an ongoing clinical trial for the Covid-19 vaccine. More recently, the university has released news of its collaboration with Thermo Fisher Scientific as it looks to discover an immune Covid-19 response pre- and post-vaccination.

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Drug Discovery World

AUGUST 7, 2024

Ashu Singhal and Sajith Wickramasekara , co-founders of Benchling, explore how AI’s true promise for the pharmaceutical industry can only be realised if the entire pharmaceutical R&D lifecycle is supported. Advancements in AI also have the potential to address key challenges in clinical trials.

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The Pharma Data

NOVEMBER 27, 2020

This week, another pharma company revealed a new technology device that can detect if a patient is infectious or not, while the Russian government published results of its Sputnik V vaccine, claiming it is more than 95 per cent efficient 42 days after the first dose.

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Advarra

JULY 19, 2022

The sponsor is the pharmaceutical company conducting the trial. If you mean using a different contract research organization (CRO) for the different phases of clinical trials – that’s different. Also consider CRO oversight, trial management, data handling and record keeping, as well as allocation of responsibilities.

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Drug Discovery World

FEBRUARY 20, 2024

Industry experts explain how blockchain can fundamentally enhance clinical trials. Obtaining consent from patients or healthy volunteers is a fundamental requirement for enrolling participants on to clinical trials. Along the study, patients are usually reconsented multiple times following a change in the trial protocol, eg.

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Drug Discovery World

FEBRUARY 20, 2024

Industry experts explain how blockchain can fundamentally enhance clinical trials. Obtaining consent from patients or healthy volunteers is a fundamental requirement for enrolling participants on to clinical trials. Along the study, patients are usually reconsented multiple times following a change in the trial protocol, eg.

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Drug Discovery World

JANUARY 26, 2023

DDW Editor Reece Armstrong takes a look at the pharmaceutical research and development market in 2023 and asks key opinion leaders what challenges and trends will emerge throughout the year. As such, 2022 saw a marked fall in ROI for global pharmaceutical companies and their research and development activities.

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DrugBank

JUNE 27, 2024

Currently, about one-third of recent drug approvals and 25% of the pharmaceutical industry's annual revenue is coming from repurposed drugs.This trend is being championed industry-wide, by public organizations and nonprofits, with numerous small companies diving in and academic publications on the subject showing great popularity.  

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Drug Discovery World

AUGUST 8, 2023

In the global pharmaceuticals market, India ranks third worldwide for production by volume and the domestic pharmaceutical market is expected to reach US$120-130 billion by 2030 1. Similarly, The Times of India says that branded generic medicines have “long fuelled India’s pharmaceutical exports” 4.

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Drug Discovery World

MAY 7, 2024

It’s doing this by collaborating with companies and providing access to expertise and facilities across 11 specialist research platforms that include things like organoid development, human challenge models, diagnostics, randomised controlled trials, hits to leads and more.

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Drug Discovery World

APRIL 19, 2023

Breaking the barrier Earlier this year, two drugs demonstrated slowed disease progression in large-scale clinical trials for ALS and Alzheimer’s. Accurate biomarkers are necessary for identifying patient subpopulations and enrolling them in clinical trials for drugs that are specifically designed for their disease.

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Drug Discovery World

JANUARY 24, 2024

Fibrocor is on track to complete all IND-enabling work to support IND filing and initiation of clinical trials in 2024. Once the big pharma companies join the race for a specific disease or target, the window of opportunity to be successful as an independent biotech company is already closed.

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DrugBaron

OCTOBER 17, 2022

Over the next few years, the practice of asset-centric investing was honed through various iterations all designed to counter the inherent progression bias that damages returns in pharmaceutical R&D. Doing that allowed the creation of new tools that are appropriate to deploy much later in the pharmaceutical R&D process.

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Drug Discovery World

MAY 29, 2024

The project will combine Oxford’s academic research capabilities with SpyBiotech’s proprietary SPYVLP platform technology to advance three vaccine candidates targeting EBV and test these in a Phase I clinical trial. We see a great need for a vaccine against EBV.”

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Drug Discovery World

AUGUST 5, 2022

An increasing number of academic groups, start-ups, biotechs and small pharma companies are turning to external consultants for professional programme management support and guidance to help them progress their ideas into medicines for patients. Why sponsors use external consultants. About the author: Ian Hollingsworth M.Sc.

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Drug Discovery World

JANUARY 5, 2023

There is a real danger for companies simply reacting to the latest EMA mandates, such as the specifics of how data will look under the EU’s eventual implementation of Identification of Medicinal Products (IDMP), and the perceived ‘watering down’ of data-driven process requirements via the shift to Digital Application Dataset Integration (DADI).

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Drug Discovery World

AUGUST 16, 2022

These observations may come to light in the clinic, but these disparities can be attributed to every phase of the drug development pipeline – clinical trials, translational research and, ultimately, drug discovery. . Additionally, the lack of diversity in patients participating in clinical trials can also contribute to cancer disparities.

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The Open Targets Blog

OCTOBER 24, 2023

Several key publications have shown that medicines with genetic evidence to support the link between target and disease have a higher chance of success in clinical trials, especially phase II safety trials.  We released the package on my personal GitHub so that I could keep updating it in the future.

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Drug Discovery World

JULY 19, 2023

Huge advancements in areas such as oncology include the advent of BioNTech’s mRNA cancer vaccine trials in the UK as soon as 2023. Pharmaceuticals and drug discovery have had something of an IP-intensive reputation for many years now, with knowledge sharing appearing to be a far-off ideal.

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