Drug Discovery World

SEPTEMBER 26, 2022

It’s why pharmaceutical companies will often spend up to 10 years and upwards of $1 billion before receiving regulatory approval for a drug. A report by the medical charity LifeArc 1 puts the timeframe for a therapy brought to market through repurposing methods at anywhere from one to three years. However, challenges remain.

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Drug Discovery World

MARCH 14, 2024

Pharmaceutical company Promontory Therapeutics has completed enrolment of its Phase II clinical trial of lead therapeutic candidate, PT-112, in patients with late-line metastatic castration-resistant prostate cancer (mCRPC).

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Drug Target Review

JUNE 19, 2024

The mission of Lineage Cell Therapeutics is to deliver on some of the early promises of cell therapy. Cell therapy as a concept is a wonderful idea, but many of the early efforts never generated the kind of clinical data that gets people excited and leads to new medicines. Hearing aids also have all sorts of deficits.

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Drug Discovery World

MAY 6, 2024

Europe is traditionally a life sciences powerhouse, with a strong tradition in pharmaceutical discovery. The oldest, still active pharmaceutical company worldwide, Merck, started life in 1668 in Darmstadt, Germany. Members of the European Federation of Pharmaceutical Industries and Associations (EFPIA) spent €41.5

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Drug Discovery World

JUNE 2, 2023

AI-designed monoclonal antibody ‘redirects’ the immune system Immuno-oncology company Aulos Bioscience has revealed interim results from an ongoing Phase I/II trial of monoclonal antibody AU-007 in solid tumours.

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Drug Discovery World

FEBRUARY 13, 2024

Often this can be drug approvals, exciting research into hard-to-treat indications, or even regulatory updates that enable players within the sector to utilise the latest technologies and drive therapies to market faster, ultimately benefitting patients. But is AI the answer to the industry’s development challenges?

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DrugBank

MARCH 7, 2024

Pharmaceutical researchers, in particular, have a keen interest in understanding the unfolding dynamics of this market. Inspired by its success, pharmaceutical companies are pursuing the development of drugs with similar therapeutic profiles, aiming to expand treatment options.

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Drug Discovery World

JULY 5, 2023

Through such therapies, slowly, hesitatingly, some people are using the word ‘cure’ with a few individual cancer patients, which is something the field has avoided for decades. These types of therapies are often more effective and have fewer side effects. We’re starting to see that this goal is realisable.

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Drug Target Review

FEBRUARY 1, 2024

This can present challenges when attempting to recruit an enriched patient population for clinical trials. Historically, what has limited investor interest in funding neurological and psychiatric therapies in development? We were able to license a molecule from a multi-national pharmaceutical company.

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DrugBank

AUGUST 15, 2024

To effectively navigate this ecosystem and expedite the development of new therapies, collaboration between the pharmaceutical industry and academia is proving increasingly vital. This includes funding large-scale clinical trials and establishing robust manufacturing/distribution networks.

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Drug Target Review

AUGUST 6, 2024

Liver Fibrosis : Targeted therapies using ADCs could help reduce liver fibrosis and prevent the progression to cirrhosis. How do companies prioritise their R&D investment between oncology and other therapeutic areas for ADCs? How do companies prioritise their R&D investment between oncology and other therapeutic areas for ADCs?

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Drug Discovery World

DECEMBER 28, 2023

In most cases, clinical trial data for paediatric patients is limited and even therapies identified in early development have even been terminated without paediatric testing – simply because they were found to be unsuccessful in older patients. We owe nothing less to them. That could be a missed opportunity.

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Drug Discovery World

JULY 15, 2024

This bodes well for potential future research and therapies,” she adds. Ariceum was presenting a poster demonstrating findings on the discovery of novel macrocyclic peptide radioligands for tumour therapy by mRNA display. András Strassz expressed that at Heidelberg Pharma, the goal is to make Amanitin available as a cancer therapy.

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Drug Discovery World

JULY 11, 2022

Pharmaceutical company Novo Nordisk has announced positive results for its prophylactic treatment targeting people living with haemophilia A or B with inhibitors. . The company’s concizumab treatment is an anti-tissue factor pathway inhibitor (TFPI)? The treatment of haemophilia is complex and no one treatment fits all, ” ?

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Drug Discovery World

MAY 15, 2024

Dr Catherine Beech , CEO at Exonate and Dr Pete Adamson , CSO at Breye Therapeutics discuss the need for better therapies to treat diabetic retinal disease and current progress in the field. Selective targeting would enable the therapy to treat the disease whilst not impacting the natural processes of VEGF. In 2019 there were >14.2

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Drug Discovery World

MARCH 13, 2024

Singapore is among a few countries worldwide whose pharmaceutical export value far exceed the import value. The government’s Biomedical Sciences (BMS) initiative was launched in June 2000, focused on boosting industries such as pharmaceuticals, biotechnology, medical technology, and healthcare.

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Drug Discovery World

JULY 18, 2022

He has 25 years’ legal experience in intellectual property (IP) and more than 25 years’ experience in the pharmaceutical, biotechnological, and chemical fields. I love innovation and working with incredible minds in the pharmaceutical and life science fields who create amazing new technologies and methods of treatment,” says Groetken.

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Drug Discovery World

FEBRUARY 10, 2023

Scandinavia represents one of the most exciting but perhaps underrepresented markets for the discovery and development of pharmaceuticals. Sweden remains Scandinavia’s powerhouse market for pharmaceutical research and development. Sweden remains Scandinavia’s powerhouse market for pharmaceutical research and development.

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The Pharma Data

FEBRUARY 25, 2021

Takeda Provides Updates on Phase 1/2 Clinical Trials of Novavax’ and Moderna’s COVID-19 Vaccine Candidates in Japan. – Phase 1/2 immunogenicity and safety trials designed to include 200 healthy Japanese adults followed for 12 months after second vaccination. TAK-919 clinical trial. TAK-019 clinical trial.

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Drug Discovery World

OCTOBER 16, 2023

A company within this ecosystem is STORM Therapeutics, a clinical stage biotechnology company creating novel small molecule therapies that inhibit RNA modifying enzymes (RME) for use in oncology and other diseases. billion in funding. billion in funding. Northern Ireland “Northern Ireland is a medtech super-hub,” says Saleko.

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Drug Discovery World

JANUARY 31, 2023

Ideally, it encapsulates every stage of drug development including drug candidate identification, clinical trials establishing efficacy, manufacturing processes, and supply chain activities for delivering these therapies to patients. Discrepancies are also exacerbated as large biopharma companies grow through acquisitions.

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DrugBank

MARCH 15, 2024

Eli Lilly's Triumph: Pioneering Solutions in Weight Management Eli Lilly's remarkable achievement with its drug Mounjaro (tirzepatide) in the fourth quarter of 2023 has sent ripples of excitement through the pharmaceutical industry. This has caused a great deal of hesitation from pharmaceutical companies in the past.

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Drug Discovery World

OCTOBER 20, 2022

Japan continues to be one of the largest pharmaceutical markets in the world, despite what the International Trade Administration described as ‘a challenging business landscape due to demographics’ 1. Overview . Investment and collaboration . Regulatory .

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Drug Discovery World

AUGUST 1, 2023

The deal makes sense given Catamaran’s focus on using synthetic biology and non-viral cell engineering to develop highly potent allogeneic, cryopreserved CAR-NK cell therapies that target challenging cancers, including solid tumours.

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Drug Discovery World

JANUARY 22, 2024

Despite the distance the biomedical world has come when it comes to improving protective measures for people participating in clinical trials, Welsh says there are still many areas where the goals of public health and pharmaceutical/medical corporations are in conflict.

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PPD

MARCH 26, 2024

The PPD clinical research business of Thermo Fisher Scientific conducts an annual survey of more than 150 leaders at pharmaceutical companies around the globe to assess trends in drug discovery and development, including preferences around outsourcing and functional service provider (FSP) utilization.

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The Pharma Data

JANUARY 12, 2021

a leader in precision medicine and artificial intelligence (AI)-enabled patient-centric oncology clinical trial enrollment, announced today it has launched its SYNERGY-AI Oncology Clinical Trial Command Center (OCTCC) with the mission to disrupt and accelerate the clinical trial enrollment process.

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Drug Discovery World

SEPTEMBER 28, 2023

Ongoing impactful trials are investigating the potential for microbiome-based diagnostic tests for endometriosis 5 and PCOS 6 using blood, faecal, vaginal, and/or endometrial samples. For example, one clinical trial is using PCR to assess microbiota composition before and after a series of interventions for PCOS 7.

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Drug Target Review

JANUARY 8, 2024

Contrary to popular belief, ageing is not caused by just random wear and tear of our bodies over time but is instead caused by a discrete set of biological mechanisms that we now better understand and can target with therapies. a commercial stage pharmaceutical company. acquired by Teva Pharmaceuticals in 2014.

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Drug Discovery World

JULY 2, 2024

Many of the more recent companies to launch in Switzerland have grown out of, developed assets from, or received financial support from the established pharmaceutical corporations in the country. For example, biotechs Actelion and Light Chain Bioscience/Novimmune were both started by Roche scientists.

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Conversations in Drug Development Trends

DECEMBER 7, 2023

Amidst a shifting clinical landscape characterized by increasingly complex trial designs and growing patient subpopulations, many contract research organizations (CROs) have adopted a “one-stop-shop” strategic approach. Moreover, these delays impact getting potentially lifesaving therapies to patients in need.

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Predictive Oncology

FEBRUARY 7, 2023

“We’re providing that richness of tumor diversity and the population diversity that normally the companies will not be able to see until they are in a clinical trial and [the drug is] challenged against a multitude of different patients.” According to Bush, this will get medicines to patients faster.

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Agency IQ

FEBRUARY 12, 2024

BY RACHEL COE, MSC | FEB 7, 2024 10:21 PM CST The Bespoke Gene Therapy Consortium A collaborative effort, the Bespoke Gene Therapy Consortium (BGTC) was launched in October 2021 to “accelerate development of gene therapies for the 30 million Americans who suffer from a rare disease.”

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The Pharma Data

MAY 5, 2022

1 Clinical trials for new therapies in AML are becoming increasingly lengthy to complete based on the traditional clinical endpoint of survival. “Measuring MRD as a surrogate endpoint may help forge a path to bring new AML therapies to patients quickly.”

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The Pharma Data

JANUARY 3, 2021

03, 2021 (GLOBE NEWSWIRE) — EyePoint Pharmaceuticals, Inc. NASDAQ: EYPT), a pharmaceutical company committed to developing and commercializing innovative ophthalmic products, today announced that Ocumension Therapeutics, a China-based ophthalmic pharmaceutical company traded on the Stock Exchange of Hong Kong (1477.HK),

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The Pharma Data

MARCH 22, 2021

VISION trial findings to be presented at upcoming medical meeting, with regulatory submissions in the US and EU anticipated in 2021. Novartis is committed to reimagining prostate cancer through targeted radioligand therapy with 177 Lu-PSMA-617. The safety profile was consistent with data reported in previous clinical studies 1.

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The Pharma Data

JANUARY 12, 2021

LONDON, UK / ACCESSWIRE / January 13, 2021 / Hemogenyx Pharmaceuticals plc (LSE:HEMO), the biopharmaceutical group developing new therapies and treatments for blood diseases, is pleased to announce that it has successfully completed the development of its CDX antibody with a leading global pharmaceutical company (“GlobalCo”).

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