Drug Discovery World

JULY 11, 2024

Over the last year Closed Loop Medicine has published clinical trial data validating use of its technology for personalised treatment of hypertension, and entered several partnerships with pharmaceutical companies.

Pharmaceutical Companies 147

Pharmaceutical Companies Clinical Trials Engineering Treatment 147

H1 Blog

DECEMBER 4, 2023

As the pharmaceutical and biotech industries continue to push for faster drug development, the importance of equity and diversity in clinical trial recruitment cannot be overlooked. With the rise of digital health and data, there are endless possibilities for reaching vulnerable populations and improving access to treatment.

Clinical Trials 59

Clinical Trials Trials Pharmaceutical Companies Pharmaceuticals 59

Drug Discovery World

FEBRUARY 21, 2024

In October 2023, pharmaceutical company NKGen Biotech released data from its Phase I clinical trial on the use of its investigational natural killer therapy, SNK01, to treat patients with Alzheimer’s disease. RA: What are the clinical benefits of using the patient’s own cells as a treatment?

Therapies 306

Therapies Treatment Trials Disease 306

Drug Discovery World

JANUARY 23, 2024

Solving bottlenecks in precision medicine R&D Medical trials underpin modern healthcare yet clinical research is an incredibly complex and time-consuming process for both patients and companies running trials, including pharmaceutical companies and emerging biotech startups.

Clinical Trials 130

Clinical Trials Pharmaceutical Companies Trials Drug Development 130

Vial

JUNE 24, 2024

Contract research organizations (CROs) and pharmaceutical companies can leverage these cutting-edge technologies to streamline clinical trials and introduce automation in drug discovery. As clinical trials grow in complexity, the volume of data being gathered and utilized for these studies is expanding.

Clinical Trials 52

Clinical Trials Trials Clinical Research Regulations 52

Antidote

JANUARY 3, 2024

While the primary goal of clinical trials is to help identify potential new treatments that improve people's health and save lives, it's the unfortunate truth that the patient experience is often not prioritized.

Clinical Trials 52

Clinical Trials Trials Pharmaceutical Companies Pharmaceuticals 52

Drug Discovery World

APRIL 25, 2023

The decision marked the first advance in first-line treatments for BTC in over 10 years. We will continue to invest behind our pipeline and recent launches while continuing to improve profitability.

Pharmaceutical Companies 245

Pharmaceutical Companies Marketing Trials Treatment 245

Drug Discovery World

NOVEMBER 29, 2023

Researchers have created a mathematical model that can accurately depict Alzheimer’s disease progression in individual patients, paving the way for personalised treatment and faster development of therapies. These findings closely matched the results of the corresponding real-life clinical trials.

Drug Development 130

Drug Development Pharmaceutical Companies Drugs FDA Approval 130

Drug Discovery World

MARCH 14, 2024

Pharmaceutical company Promontory Therapeutics has completed enrolment of its Phase II clinical trial of lead therapeutic candidate, PT-112, in patients with late-line metastatic castration-resistant prostate cancer (mCRPC). Patients with bone-only metastatic disease are also included in the study.

Clinical Trials 130

Clinical Trials Pharmaceutical Companies Drugs FDA 130

Drug Discovery World

JANUARY 29, 2024

Utilising diverse data in clinical trials for drug discovery: Key speakers from pharma and industry discussed the integration of diverse data in clinical trials, emphasising its role in accelerating drug discovery processes for more effective and personalised treatments.

Clinical Trials 147

Clinical Trials Pharmaceutical Companies Trials Pharmaceuticals 147

Drug Discovery World

AUGUST 12, 2022

New insights into melanoma, a company transition into life sciences and a Lyme disease vaccine are some of the stories in this week’s news round-up. Pfizer launches Phase III trial for Lyme disease vaccine?? . Oxeia Biopharmaceuticals encouraged by concussion treatment? .

Vaccine 130

Vaccine Pharmaceutical Companies Clinical Trials Drugs 130

Drug Discovery World

APRIL 17, 2024

The Bios Innovation Circle is aimed at empowering the success of biotech and life science companies, investors, pharmaceutical companies, clinical research organisations and other innovative solution providers to accelerate development and bring life-saving treatments to the market faster.

Science 130

Science Pharmaceutical Companies Clinical Research Therapies 130

Drug Discovery World

APRIL 14, 2023

The headlines our attention this week all represent significant breakthroughs in the treatment of various diseases and could make a huge difference to the lives of these patients. There is also new hope for sepsis treatment and for preventing cardiovascular disease in people with HIV thanks to recent research.

Vaccine 130

Vaccine Clinical Trials Drugs Pharmaceutical Companies 130

Drug Discovery World

MARCH 2, 2023

This has left many living with rare diseases without available or approved treatments and support for their conditions. ” The role of AI in rare disease clinical trials might hold the key to helping the UK achieve this vision. This can aid early diagnosis and treatment of rare diseases.

Drug Development 130

Drug Development Disease Clinical Trials Drugs 130

Drug Discovery World

SEPTEMBER 26, 2022

It’s why pharmaceutical companies will often spend up to 10 years and upwards of $1 billion before receiving regulatory approval for a drug. Perhaps the biggest benefit drug repurposing brings is its potential to get treatments to patients faster than traditional means of drug discovery. However, challenges remain.

Pharmaceutical Companies 130

Pharmaceutical Companies Drugs Pharmaceuticals Clinical Trials 130

Drug Discovery World

MAY 3, 2023

Vicore Pharma, a Swedish clinical-stage pharmaceutical company unlocking the potential of angiotensin II type 2 receptor agonists (ATRAGs), has dosed its first patient with C21 in a clinical study of endothelial dysfunction. Vicore Pharma states that results from the trial are expected in Q4, 2023.

FDA Approval 130

FDA Approval Trials Pharmaceutical Companies Disease 130

Drug Discovery World

JULY 5, 2023

Precision oncology supports targeted therapeutic treatments by determining the specific molecular characteristics of a tumour – the molecular phenotype, as it’s called – to obtain an in depth understanding of the patient’s unique cancer and using it to specifically target the patient’s cancer on a molecular level.

Research 246

Research Immune Response Pharmaceutical Companies Treatment 246

Drug Discovery World

JUNE 2, 2023

AI-designed monoclonal antibody ‘redirects’ the immune system Immuno-oncology company Aulos Bioscience has revealed interim results from an ongoing Phase I/II trial of monoclonal antibody AU-007 in solid tumours. The post This week in drug discovery (29 May – 2 June) appeared first on Drug Discovery World (DDW).

Pharmaceutical Companies 130

Pharmaceutical Companies Clinical Trials Drugs Pharmaceuticals 130

H1 Blog

DECEMBER 18, 2023

How will AI impact clinical trials? Every year, we take a look at annual predictions to help life sciences, pharmaceutical, and healthcare companies understand larger industry trends and dynamics to prepare for the new year. FinTech will merge with HealthTech to provide more robust patient experiences and aid in treatment plans.

Trials 64

Trials Clinical Trials FDA Pharmaceutical Companies 64

Drug Discovery World

NOVEMBER 11, 2022

It wasn’t all bad news, however, as top pharma CEOs committed to reducing the industry’s carbon emissions and a new treatment for Graft vs Host Disease could be on the horizon. The drug discovery community also gained new insights into the inner workings of a new class of cancer drugs and how monkeypox adapts to evade treatments. .

Pharma Companies 130

Pharma Companies Drugs Pharmaceutical Companies Disease 130

Drug Discovery World

SEPTEMBER 28, 2023

The microbiome also is being explored as a metric to gauge therapeutic efficacy of symptom-based treatment for these conditions. For example, one clinical trial is using PCR to assess microbiota composition before and after a series of interventions for PCOS 7.

Clinical Trials 162

Clinical Trials Regulations Trials Drug Development 162

Drug Discovery World

DECEMBER 28, 2023

But I also recall other moments that made me painfully aware that significant efforts are needed in the treatment of children with cancer. To date, much of the conversation in oncology research and development has focused on treatments for adults. I was impressed by his determination and proud to be part of his team.

Research 130

Research Clinical Trials Hospitals Trials 130

The Pharma Data

SEPTEMBER 15, 2020

Biopharma and pharmaceutical companies developing treatments and vaccines have long faced operational challenges that cost time and money while draining resources from the important work of changing lives. In spring 2020, Avantor’s clinical services team provided treatment developers with support for a fast-track study.

Clinical Trials 52

Clinical Trials Trials Pharmaceutical Companies Vaccine 52

DrugBank

MARCH 7, 2024

Inspired by its success, pharmaceutical companies are pursuing the development of drugs with similar therapeutic profiles, aiming to expand treatment options. Key Players and Challenges For pharmaceutical giants like Novo Nordisk and Eli Lilly, 2024 presents both opportunities and challenges.

Pharmaceutical Companies 80

Pharmaceutical Companies Pharmaceuticals Clinical Trials Pharmacokinetics 80

The Pharma Data

OCTOBER 9, 2021

The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the submission of a supplemental Biologics License Application (sBLA) to the U.S. 2 PsA can be a challenging disease to treat especially in younger populations, reinforcing the need for additional treatment options. A decision from the U.S.

FDA Approval 52

FDA Approval FDA Treatment Pharmaceutical Companies 52

Drug Target Review

AUGUST 6, 2024

Autoimmune diseases : Rheumatoid Arthritis : ADCs targeting specific immune cells or inflammatory mediators can provide more precise treatment options with potentially fewer side effects. Obesity : By targeting adipose tissue or specific metabolic pathways, ADCs could offer new treatments for obesity and related metabolic disorders.

Pharmaceutical Companies 117

Pharmaceutical Companies Therapies Disease Treatment 117

Conversations in Drug Development Trends

MAY 14, 2024

As the strategists for Worldwide Clinical Trials’ rare disease sponsors, we design customized solutions that make a difference in achieving successful outcomes. This philosophy is encapsulated in our belief: “If you’ve seen one trial for a rare indication, you’ve seen one trial.”

Disease 81

Disease Clinical Trials Trials Pharmaceutical Companies 81

The Pharma Data

FEBRUARY 25, 2021

Takeda Provides Updates on Phase 1/2 Clinical Trials of Novavax’ and Moderna’s COVID-19 Vaccine Candidates in Japan. – Phase 1/2 immunogenicity and safety trials designed to include 200 healthy Japanese adults followed for 12 months after second vaccination. TAK-919 clinical trial. TAK-019 clinical trial.

Clinical Trials 52

Clinical Trials Trials Vaccine Pharmaceutical Companies 52

The Pharma Data

OCTOBER 20, 2020

Led by scientists at Imperial College London, people in this challenge trial will be guaranteed treatment if they become ill. The United States says human challenge trials might be too risky or unnecessary. Challenge trials have a long history, going back to Edward Jenner’s development of a smallpox vaccine in 1796.

Trials 52

Trials Vaccine Virus Pharmaceutical Companies 52

The Pharma Data

FEBRUARY 8, 2021

Janssen Announces Treatment with ERLEADA ® (apalutamide) Significantly Improved Overall Survival in Patients with Metastatic Castration-Sensitive Prostate Cancer. ERLEADA ® is an androgen receptor (AR) inhibitor indicated for the treatment of patients with nmCRPC and for the treatment of patients with mCSPC. 10 months. [5]

Treatment 52

Treatment Pharmaceutical Companies Therapies Pharmaceuticals 52

The Pharma Data

MARCH 7, 2022

Astellas”) today announced topline results from the Phase 3 SKYLIGHT 4™ clinical trial investigating the long-term safety of fezolinetant, an investigational oral, nonhormonal compound being studied for the treatment of moderate to severe vasomotor symptoms associated with menopause (VMS) which will support future regulatory filing submissions.

Treatment 52

Treatment Clinical Trials Trials Pharmaceutical Companies 52

Drug Discovery World

DECEMBER 22, 2022

This not only has public health ramifications, but also impacts vaccine efficacy trials, which hinge upon active transmission of a disease within a population to gather meaningful data. For instance, responsive clinical trials can use surveillance data to identify geographic areas and communities that are at high risk for disease.

Vaccine 130

Vaccine Disease Clinical Trials Trials 130

Drug Discovery World

MAY 30, 2023

The Janssen Pharmaceutical Companies of Johnson & Johnson have submitted a Type II variation application to the European Medicines Agency (EMA) seeking approval of Carvykti (ciltacabtagene autoleucel; cilta-cel) for relapsed and lenalidomide-refractory multiple myeloma.

Therapies 130

Therapies Pharmaceutical Companies Treatment Pharmaceuticals 130

Drug Discovery World

MARCH 5, 2024

In her day-to-day role, she is responsible for the development of UCB’s epilepsy discovery strategy, working with researchers to advance understanding of epilepsies while ensuring candidates for a future clinical treatment pipeline to improve the lives of those living with the condition. LR: Can you share the latest epilepsy research trends?

Disease 147

Disease Treatment Research Pharmaceutical Companies 147

The Pharma Data

DECEMBER 17, 2020

18, 2020 /PRNewswire/ — Camurus AB (NASDAQ STO: CAMX) announced today that the Swiss agency for therapeutic products, Swissmedic, has approved weekly and monthly Buvidal ® prolonged release buprenorphine for the treatment of opioid dependence in adults and adolescents from 16 years of age. LUND, Sweden , Dec. About Buvidal.

Treatment 52

Treatment Clinical Trials International Pharmaceutical Companies 52

The Pharma Data

OCTOBER 9, 2021

Takeda Pharmaceutical Company Limited ( TSE:4502/NYSE:TAK ) (“Takeda”) today announced the U.S. The committee also voted unanimously to recommend use of maribavir for the treatment of refractory CMV infection and disease without genotypic resistance to ganciclovir, valganciclovir, foscarnet or cidofovir in transplant recipients.

FDA 52

FDA Treatment Disease Pharmaceutical Companies 52

DrugBank

AUGUST 15, 2024

To effectively navigate this ecosystem and expedite the development of new therapies, collaboration between the pharmaceutical industry and academia is proving increasingly vital. This includes funding large-scale clinical trials and establishing robust manufacturing/distribution networks.

Drug Development 80

Drug Development Clinical Trials Drugs Therapies 80