Vial

JUNE 24, 2024

Contract research organizations (CROs) and pharmaceutical companies can leverage these cutting-edge technologies to streamline clinical trials and introduce automation in drug discovery. As clinical trials grow in complexity, the volume of data being gathered and utilized for these studies is expanding.

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Drug Discovery World

AUGUST 12, 2022

Pfizer has launched a Phase III clinical trial of a vaccine to protect people against Lyme disease, in collaboration with pharmaceutical company Valneva. . The trial will enrol up to 6,000 participants aged five years and older and will be conducted across 50 sites where Lyme disease is highly endemic. February 2022.

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Drug Discovery World

DECEMBER 9, 2022

A new type of targeted medicine has shown ‘remarkable’ benefits for patients with advanced breast cancer in a major Phase III clinical trial. . It was discovered by pharmaceutical company AstraZeneca following a programme of drug discovery research at The Institute of Cancer Research, London. . The CAPItello-291 trial.

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PPD

AUGUST 16, 2023

The COVID-19 pandemic rapidly accelerated the adoption of hybrid and decentralized clinical trial (DCT) models. However, as the world settles into its post-pandemic state and returns to pre-pandemic paradigms in many areas, the pharmaceutical industry remains dedicated to moving beyond traditional, centralized clinical trial constructs.

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H1 Blog

DECEMBER 4, 2023

As the pharmaceutical and biotech industries continue to push for faster drug development, the importance of equity and diversity in clinical trial recruitment cannot be overlooked. Data is a powerful tool in identifying and reaching vulnerable populations for clinical trials.

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Drug Discovery World

MARCH 8, 2024

MSRD, a member of the Otsuka family of pharmaceutical companies, identifies and supports early-stage opportunities that can change the landscape of treatments for mental illness and renal disorders. FIB918 is now in the IND-enabling phase and Phase I clinical trials of the monoclonal antibody are targeted to start in late 2025.

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Antidote

JANUARY 3, 2024

While the primary goal of clinical trials is to help identify potential new treatments that improve people's health and save lives, it's the unfortunate truth that the patient experience is often not prioritized.

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Drug Discovery World

JANUARY 23, 2024

Solving bottlenecks in precision medicine R&D Medical trials underpin modern healthcare yet clinical research is an incredibly complex and time-consuming process for both patients and companies running trials, including pharmaceutical companies and emerging biotech startups.

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Drug Discovery World

JANUARY 12, 2023

Here, Thomas reflects specifically on Anita Cooper’s prediction relating to the importance of clinical trials. . Following the launch of Protas, DDW spoke with Protas Chief Executive, Professor Sir Martin Landray, who echoed Cooper’s emphasis on the importance of clinical trial design.

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Conversations in Drug Development Trends

MAY 23, 2024

By: Sarah Bly, Regulatory Science and Innovation and Matt Cooper, Executive Director, Therapeutic Strategy Lead, Oncology The European Union (EU) presents a unique set of regulatory challenges and opportunities for clinical trials in oncology. Increased Transparency : Ensures that information on clinical trials is more accessible.

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Drug Discovery World

MARCH 14, 2024

Pharmaceutical company Promontory Therapeutics has completed enrolment of its Phase II clinical trial of lead therapeutic candidate, PT-112, in patients with late-line metastatic castration-resistant prostate cancer (mCRPC).

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PPD

APRIL 30, 2024

31, 2022, the EU Clinical Trial Regulation (EU CTR) 536/2014 became applicable, heralding a new era for clinical trials in the European Union (EU). In addition, the constant evolution of EMA and Clinical Trials Coordination Group (CTCG) guidelines requires constant attention.

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Drug Discovery World

MARCH 6, 2024

The fact that 100+ clinical trials in Alzheimer’s have failed to demonstrate clinical efficacy should warn us that this is too simplistic an approach in neurological diseases. This is wholly unsurprising. This has been the real failure of some areas of CNS drug discovery. This has been the real failure of some areas of CNS drug discovery.

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Drug Discovery World

JUNE 20, 2024

Deepika Khedekar investigates the use of LLMs in clinical trials and how we can overcome the potential challenges to their wider application. Clinical trials make up a large part of this investment, and yet 95% of them fail 2. A single phase III clinical trial can rack up to 3.56 million data points 5.

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Drug Discovery World

JANUARY 29, 2024

Utilising diverse data in clinical trials for drug discovery: Key speakers from pharma and industry discussed the integration of diverse data in clinical trials, emphasising its role in accelerating drug discovery processes for more effective and personalised treatments.

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H1 Blog

DECEMBER 18, 2023

How will AI impact clinical trials? Every year, we take a look at annual predictions to help life sciences, pharmaceutical, and healthcare companies understand larger industry trends and dynamics to prepare for the new year. Will FDA legislation improve diversity? What platforms will key opinion leaders adopt?

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Drug Discovery World

NOVEMBER 11, 2022

Seven pharmaceutical companies have announced a joint initiative to reduce near-term emissions and help develop net zero health systems. . The Task Force will now take collective action to address emissions across three priority areas: supply chains, patient care pathways and clinical trials. Three areas of priority .

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Drug Discovery World

NOVEMBER 29, 2023

The simulator could also be used by pharmaceutical companies to rapidly test multiple drug therapies and patient scenarios, increasing the speed and cost of drug development. These findings closely matched the results of the corresponding real-life clinical trials.

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Drug Discovery World

APRIL 17, 2024

The Bios Innovation Circle is a venture studio and strategic hub designed to catalyse the growth of start-ups, growing biotech and life science companies in a cost-effective and equity-sparing manner.

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DS in Pharmatics

SEPTEMBER 25, 2023

A robust Quality Management System (QMS) is an important aspect of a Pharmaceutical company as it demonstrates a company’s Senior Management commitment to Quality. QMS instills the mindset that assures that the company will have qualified and trained individuals who focus on “Quality” throughout the lifecycle of the product.

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Drug Discovery World

MAY 3, 2023

Vicore Pharma, a Swedish clinical-stage pharmaceutical company unlocking the potential of angiotensin II type 2 receptor agonists (ATRAGs), has dosed its first patient with C21 in a clinical study of endothelial dysfunction. Vicore Pharma states that results from the trial are expected in Q4, 2023.

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Drug Discovery World

FEBRUARY 21, 2024

In October 2023, pharmaceutical company NKGen Biotech released data from its Phase I clinical trial on the use of its investigational natural killer therapy, SNK01, to treat patients with Alzheimer’s disease. RA: How encouraged are you by these Phase I data? RA: You’ve now received clearance for a Phase I/IIa study.

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Drug Discovery World

SEPTEMBER 26, 2022

It’s why pharmaceutical companies will often spend up to 10 years and upwards of $1 billion before receiving regulatory approval for a drug. This is a stark contrast to the often decade-long projects that pharmaceutical companies undertake to bring a drug to market.

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Drug Discovery World

JULY 8, 2022

Pharmaceutical company Novavax is attempting to expand the use of its Covid-19 vaccine Nuvaxovid into adolescents aged 12-17 year and as a booster dose for adults. . The company has submitted a request to Swissmedic to expand the conditional marketing authorisation (CMA) of Nuvaxovid.

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Drug Discovery World

FEBRUARY 1, 2023

Acquisition of UK innovation by US companies increased, including Pfizer’s acquisition of ReViral for an estimated £420 million, Gilead’s acquisition of MiroBio for an estimated £305 million, and Abbvie’s acquisition of DJS Antibodies for £229 million. Leading UK biotechs also achieved pivotal milestones in their development.

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Drug Discovery World

AUGUST 12, 2022

New insights into melanoma, a company transition into life sciences and a Lyme disease vaccine are some of the stories in this week’s news round-up. Pfizer launches Phase III trial for Lyme disease vaccine?? . Life sciences company PerkinElmer will divest its?Applied, billion. .

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Drug Discovery World

APRIL 25, 2023

We will continue to invest behind our pipeline and recent launches while continuing to improve profitability.

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Drug Discovery World

MAY 6, 2024

Europe is traditionally a life sciences powerhouse, with a strong tradition in pharmaceutical discovery. The oldest, still active pharmaceutical company worldwide, Merck, started life in 1668 in Darmstadt, Germany. Members of the European Federation of Pharmaceutical Industries and Associations (EFPIA) spent €41.5

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Drug Discovery World

JUNE 2, 2023

AI-designed monoclonal antibody ‘redirects’ the immune system Immuno-oncology company Aulos Bioscience has revealed interim results from an ongoing Phase I/II trial of monoclonal antibody AU-007 in solid tumours.

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Advarra

JUNE 9, 2022

Optimizing clinical trial access for potential patients is a critical goal for researchers and sponsors. Decentralized clinical trials (DCTs) can meet that need, but they come with some challenges. Designing a DCT comes with certain challenges of course, particularly when proposing to utilize outside groups or locations for the trial.

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The Pharma Data

SEPTEMBER 15, 2020

Biopharma and pharmaceutical companies developing treatments and vaccines have long faced operational challenges that cost time and money while draining resources from the important work of changing lives. Working closely with researchers, Avantor quickly developed a solution that incorporated customized kits for the clinical trial.

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The Pharma Data

MAY 7, 2021

World regulatory authorities are calling for increased transparency from the pharmaceutical industry in how they report and give access to clinical trial data. Only personally identifying information and individual patient data should be redacted from publicly available clinical trial data, wrote WHO and ICMRA. . “In

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Drug Discovery World

MARCH 2, 2023

” The role of AI in rare disease clinical trials might hold the key to helping the UK achieve this vision. AI is revolutionising clinical trials and drug developments just as it is transforming other sectors, but in order for AI to make progress in rare diseases, the UK needs further investment to increase uptake and use.

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Drug Channels

FEBRUARY 7, 2024

Tomorrow, we’ll be treated to a Senate show trial featuring pharmaceutical company executives. In reality, nearly all drug spending growth occurred due to growth in the number of people treated, prescriptions dispensed, and other nonprice factors. healthcare expenditures.

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The Pharma Data

FEBRUARY 25, 2021

Takeda Provides Updates on Phase 1/2 Clinical Trials of Novavax’ and Moderna’s COVID-19 Vaccine Candidates in Japan. – Phase 1/2 immunogenicity and safety trials designed to include 200 healthy Japanese adults followed for 12 months after second vaccination. TAK-919 clinical trial. TAK-019 clinical trial.

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DrugBank

MARCH 7, 2024

Inspired by its success, pharmaceutical companies are pursuing the development of drugs with similar therapeutic profiles, aiming to expand treatment options. Key Players and Challenges For pharmaceutical giants like Novo Nordisk and Eli Lilly, 2024 presents both opportunities and challenges.

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Drug Discovery World

MARCH 20, 2024

Around 30% of drugs show adverse reactions during human clinical trials despite promising pre-clinical studies. This signifies the technology’s potential to de-risk drug development by ensuring only the most clinically relevant leads advance to clinical trials. Backed by the FDA Modernization Act 2.0,

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