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Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry

Drug Hunter

Interestingly, among the six case studies, none use the well-known Hoveyda-Grubbs II (HG-II) catalyst in the largest scale synthesis disclosed, though several employ HG-II derivatives, highlighting the rapid evolution of catalytic methods and distinct considerations for process chemistry. Gonzalez-Bobes, F. 2023 , 66 , (8), 5377-5396.

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Process Chemistry Unleashed: A 'Fit-for-Purpose' Approach to Accelerate IND Filing

Fierce BioTech

Process Chemistry Unleashed: A 'Fit-for-Purpose' Approach to Accelerate IND Filing pesurya Thu, 07/27/2023 - 11:27 Tue, 09/05/2023 - 10:00 Resource Type Webinar Qixuan Lu Duration 60 Minutes Process chemistry plays a pivotal role in various stages of the pharmaceutical R&D cycle.

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Form and Formulation

Sygnature Discovery

These strategies are tailored to the unique characteristics of each individual Active Pharmaceutical Ingredient (API). Our talented team of scientists can assist you in crafting robust pre-clinical development strategies. This approach helps to overcome even the most complex bioavailability or stability challenges.

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Empowering women in STEM: Navigating CMC regulatory affairs

Drug Target Review

Dr Lopa Bakrania brings over 18 years of experience in pharmaceutical process chemistry and CMC regulatory affairs. On March 8th, 2025, International Womens Day, we celebrate the achievements of women in STEM, including leaders like Dr Lopa Bakrania, who are advancing pharmaceutical research and regulatory science.

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