DrugBank

AUGUST 9, 2024

Investment Trends in Pharmaceutical Research and Development Investing in the pharmaceutical sector presents a unique set of challenges and opportunities; let’s examine them in more detail.  Pharmaceutical Market Analysis The global pharmaceutical market revenue in 2024 is projected to be 1.15 billion by 2030.

Pharmaceuticals 76

Pharmaceuticals Research Pharmaceutical Companies Clinical Trials 76

Drug Target Review

FEBRUARY 1, 2024

Historically, what has limited investor interest in funding neurological and psychiatric therapies in development? Investors have historically taken a ‘guilty until proven innocent’ approach to investing in neuroscience therapies. We were able to license a molecule from a multi-national pharmaceutical company.

Therapies 104

Therapies Drug Development Disease Clinical Development 104

Drug Target Review

JUNE 19, 2024

The mission of Lineage Cell Therapeutics is to deliver on some of the early promises of cell therapy. Cell therapy as a concept is a wonderful idea, but many of the early efforts never generated the kind of clinical data that gets people excited and leads to new medicines. In some cases, cell therapy can be curative for the patient.

Therapies 84

Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

DrugBank

OCTOBER 4, 2024

Deal Structuring Deal structuring in pharmaceutical M&A requires a balance of financial, legal, and strategic considerations. Intellectual Property Valuation Valuing intellectual property (IP) assets is a critical component of pharmaceutical M&A, as these assets often represent a significant portion of a company's value.

Pharmaceuticals 80

Pharmaceuticals Pharmaceutical Companies Therapies Marketing 80

BioPharma Drive: Drug Pricing

DECEMBER 10, 2023

A new sickle cell disease therapy developed by CRISPR Therapeutics and Vertex Pharmaceuticals is now approved in the U.S. This is the story of how it came to be.

Therapies 142

Therapies Pharmaceuticals Disease 142

BioPharma Drive: Drug Pricing

OCTOBER 21, 2024

Immunotherapy and precision medicine show promise in better fighting cancer. What else does the research tell us?

Research 105

Research Therapies Pharmaceuticals 105

Drug Hunter

SEPTEMBER 17, 2023

This month features many of the big reveals from the ACS fall 2023 first disclosures including Nurix’s BTK degrader and RAPT’s CCR4 autoimmune therapy. selective inhibitor developed by Vertex Pharmaceuticals for acute pain in Phase III clinical trials. Several of the molecules making the August list are in Ph.

Clinical Trials 206

Clinical Trials Trials Therapies Pharmaceuticals 206

Drug Patent Watch

DECEMBER 17, 2024

Contract Development and Manufacturing Organizations (CDMOs) are at the forefront of this shift, playing a crucial role in bringing innovative therapies to market. Let’s dive into the world of pharmaceutical outsourcing and explore why adaptability is the key to success.

Pharmaceuticals 64

Pharmaceuticals Therapies Production Pharmaceutical Companies 64

BioPharma Drive: Drug Pricing

NOVEMBER 8, 2023

A gene editing therapy developed by Vertex Pharmaceuticals and CRISPR Therapeutics can mute sickle cell disease’s most damaging symptoms. Yet treatment may not be as simple as its dramatic benefit makes it seem.

Therapies 131

Therapies Pharmaceuticals Treatment Disease 131

BioPharma Drive: Drug Pricing

AUGUST 16, 2023

The decision stands in contrast to the agency’s plans for a would-be rival gene editing treatment from Vertex Pharmaceuticals and CRISPR Therapeutics that is also under a regulatory review.

Therapies 98

Therapies FDA Pharmaceuticals Treatment 98

Drug Discovery Today

JANUARY 13, 2020

Joint Venture to develop next generation cell and gene therapies incorporating Affimer proteins

Pharmaceuticals 100

Pharmaceuticals Therapies 100

Drug Target Review

DECEMBER 20, 2024

Artificial intelligence (AI) has revolutionised many industries, yet its adoption in pharmaceutical drug development has been notably slower. Looking ahead, 2025 could represent a major turning point for the pharmaceutical sector.

Clinical Trials 117

Clinical Trials Trials Pharmaceuticals Drug Development 117

Drug Discovery Today

AUGUST 14, 2020

Avacta has appointed Neil Bell, a highly experienced pharmaceutical and biotech industry executive, to lead the ongoing transition to a clinical stage biotech developing innovative cancer therapies

Therapies 113

Therapies Pharmaceuticals 113

Fierce BioTech

MAY 29, 2024

New Solutions for Aseptic Filling for Gene Therapy In the development of gene therapies, it is more important than ever to stay on top of the latest containment and aseptic filling solutions.

Therapies 52

Therapies Pharmaceuticals 52

Fierce BioTech

MAY 2, 2024

West Pharmaceutical Services (West) and Cytiva have teamed up to offer innovative and versatile fill finish solutions to efficiently meet the unique demands of advanced pharmaceutical applications. In this webinar, you will learn about: The challenges and risks related to the packaging and filling of high-value drug products.

Therapies 52

Therapies Packaging Pharmaceuticals Production 52

Drug Target Review

DECEMBER 5, 2024

Viral vectors have been crucial in transforming the gene therapy landscape due to their natural ability to infect cells. 1 In 2017, the US Food and Drug Administration (FDA) approved the first AAV-based gene replacement therapy (Luxturna), for Leber congenital amaurosis type 2.

Therapies 52

Therapies Virus DNA Compliance 52

Drug Target Review

AUGUST 6, 2024

Liver Fibrosis : Targeted therapies using ADCs could help reduce liver fibrosis and prevent the progression to cirrhosis. Expedited programs like the FDA’s Breakthrough Therapy Designation and Fast Track can shorten development timelines and reduce risk. CDMOs are crucial.

Therapies 117

Therapies Pharmaceutical Companies Disease Treatment 117

Drug Target Review

JULY 11, 2024

To date, there are less than 30 known surface proteins that form the basis of all approved cancer-targeted therapies of all modalities, including antibody-drug conjugates (ADCs), T-cell engagers, CAR T-cells and radiopharmaceuticals. These could be targets for antibody-drug conjugates (ADCs), bi-specific antibodies, or other therapies.

Therapies 56

Therapies RNA Pharma Companies Disease 56

Drug Target Review

JANUARY 8, 2024

Contrary to popular belief, ageing is not caused by just random wear and tear of our bodies over time but is instead caused by a discrete set of biological mechanisms that we now better understand and can target with therapies. a commercial stage pharmaceutical company. acquired by Teva Pharmaceuticals in 2014.

Science 145

Science Disease FDA Approval Clinical Trials 145

Alta Sciences

OCTOBER 21, 2024

BioPharma Dive: Pharmaceutical Research on mRNA and CAR T-Cell Therapy in Cancer — Pioneering the Future of Oncology aasimakopoulos Mon, 10/21/2024 - 13:18 Category News Tags Clinical Trials Preclinical Research Weight 1

Therapies 40

Therapies Pharmaceuticals Research Clinical Trials 40

Alta Sciences

JUNE 11, 2024

My Attendance at the 2024 Boston Society Cell and Gene Therapy Conference pmjackson Tue, 06/11/2024 - 20:49 , via Wikimedia Commons" data-entity-type="file" data-entity-uuid="c7a7fa8b-b2fe-4d84-a75e-d1ba3a4e2caf" src="[link] width="742" height="249" loading="lazy" /> Ecm85, CC BY-SA 3.0

Therapies 52

Therapies Molecular Biology Immune Response Science 52

Chemical Biology and Drug Design

SEPTEMBER 13, 2023

This review aims to provide information on cutting-edge Nano particulate-based technologies and Nano therapies for colorectal cancer. The field of cancer detection and therapy has undergone a revolution with the development of nanotechnology for targeted drug delivery.

Drugs 100

Drugs Therapies Science Pharmaceuticals 100

Chemical Biology and Drug Design

JUNE 19, 2024

Exploring the transformative impact of large language models (LLMs) in molecular biology and drug development, discussing potential areas of applications and breakthroughs in personalized therapies. While enhancing molecular biology aspects, we also address ethical concerns ensuring responsible application of these models.

Molecular Biology 100

Molecular Biology Drug Development Drugs Therapies 100

Antidote

JULY 29, 2022

billion to bring a new therapy to market. In 2019 alone, research and development spending totaled $186 billion for the global pharmaceutical industry. Between 2009 and 2018, U.S.

Clinical Trials 96

Clinical Trials Trials Therapies Pharmaceuticals 96

Drug Target Review

NOVEMBER 27, 2023

By directly interfering with the eIF4F complex, eFFECTOR’s STRIs provide a promising avenue for disrupting the core mechanisms of cancer, offering the potential to improve patient outcomes and overcome the limitations of traditional cancer therapies. Prior to Anadys Pharmaceuticals, Inc., Prior to Anadys Pharmaceuticals, Inc.,

Molecular Biology 86

Molecular Biology Therapies Pharmaceuticals Treatment 86

Drug Channels

SEPTEMBER 8, 2023

Nasir discusses how hubs help patients initiate and adhere to drug therapies. Today’s guest post comes from Nasir Ali, Chief Product Officer at CareMetx. Based on CareMetx research, he outlines the key factors that drug manufacturers value in their hub partners.

Pharmaceuticals 74

Pharmaceuticals Therapies Production Drugs 74

Drug Target Review

OCTOBER 26, 2023

Genome engineering and gene therapies that manipulate DNA sequences in cells have driven a biotechnological revolution over the past decade. Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union. Molecular Therapy 20 , 1831-1832 (2012). Nature 578 , 229-236 (2020).

Engineering 105

Engineering Virus Therapies Immune Response 105

DrugBank

MARCH 7, 2024

Pharmaceutical researchers, in particular, have a keen interest in understanding the unfolding dynamics of this market. Inspired by its success, pharmaceutical companies are pursuing the development of drugs with similar therapeutic profiles, aiming to expand treatment options.

Pharmaceutical Companies 80

Pharmaceutical Companies Clinical Trials Pharmaceuticals Therapies 80

Drug Target Review

JUNE 27, 2023

We embark on a fascinating journey through the realms of cell and gene therapy, CRISPR technology, cancer research, and the latest advancements in screening and imaging. Prepare to be captivated by the groundbreaking discoveries and innovative approaches revolutionising the field of healthcare. But it doesn’t stop there.

Drugs 97

Drugs Therapies Engineering Disease 97

Drug Channels

MARCH 22, 2024

Adam discusses how patients seeking to access specialty therapies can benefit from a digital intake approach. He then explains three ways that specialty pharmaceutical companies can use digital intake strategies to speed patient enrollment. Today’s guest post comes from Adam Stotts, SVP of Customer Success at AssistRx.

Pharmaceutical Companies 86

Pharmaceutical Companies Therapies Pharmaceuticals Drugs 86

Drug Target Review

JULY 4, 2023

These therapies have broadened treatment options for patients to expand beyond the more traditional small molecule drug alternatives. Patients and caregivers also assess the benefits offered by different therapies, weighing the progression-free survival with their off-target effects.

Small Molecule 145

Small Molecule Drugs Clinical Pharmacology Trials 145

Drug Target Review

JANUARY 23, 2024

Cell-based therapies, such as tumour-infiltrating lymphocyte (TIL) therapy, have also drawn significant attention following promising results in a melanoma trial. We anticipate this area to grow, especially cancer vaccines, with important read-outs expected across various cancer types in 2024.

Treatment 122

Treatment Immune Response Vaccine Therapies 122

The Pharma Data

MARCH 31, 2022

Bayer announced today that it is strengthening the production network of its pharmaceutical division to ensure sustainable competitiveness and support the transformation of its pharmaceutical business based on breakthrough innovation delivering long-term, sustainable business growth.

Production 52

Production Pharmaceuticals Science Therapies 52

BioPharma Drive: Drug Pricing

JUNE 4, 2024

Longer follow-up results from a mid-stage trial indicate the company’s treatment for a genetic cause of dwarfism may be competitive to an approved therapy from BioMarin Pharmaceutical.

Therapies 72

Therapies Pharmaceuticals Trials Treatment 72

Drug Hunter

JUNE 11, 2023

Thanks to decades of Nobel Prize-winning advances in chemistry, modern pharmaceutical scientists are now able to build far more complex molecules than ever before to tackle today’s healthcare crises. The small molecules drugs of today look nothing like the molecules of the 1970s.

Small Molecule 147

Small Molecule Treatment Pharmaceuticals Engineering 147

thought leadership

AUGUST 26, 2024

In the dynamic world of pharmaceuticals and biotechnology, small Sponsor companies are often the unsung heroes driving innovative therapies through the complex journey from concept to clinic.

Clinical Development 71

Clinical Development Therapies Pharmaceuticals Compliance 71

DrugBank

AUGUST 15, 2024

To effectively navigate this ecosystem and expedite the development of new therapies, collaboration between the pharmaceutical industry and academia is proving increasingly vital. An example is the collaboration between Novartis and the University of Oxford to develop a gene therapy for spinal muscular atrophy, a rare genetic disease.

Drug Development 80

Drug Development Clinical Trials Drugs Therapies 80