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A personal touch: the role of bioprinting in drug discovery

Drug Discovery World

The company hopes that through its technology, academics, life science industries and pharma industries can test and develop more personalised treatments for intricate tissue engineering and cell therapy, such as repairing damaged tissue, replacing lost biological functions, localised therapeutic solutions and complex drug formulations. .

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Preclinical systemic pharmacokinetics, dose-proportionality, and CNS distribution of the ATM inhibitor WSD0628, a novel radiosensitizer for the treatment of brain tumors [Metabolism, Transport, and Pharmacogenetics]

ASPET

Radiation therapy, a standard treatment option for many cancer patients, induces DNA double strand breaks (DSBs), leading to cell death. Ataxia telangiectasia mutated (ATM) kinase is a key regulator of DSB repair, and ATM inhibitors are being explored as radiosensitizers for various tumors, including primary and metastatic brain tumors.