CNS distribution of panobinostat in preclinical models to guide dosing for pediatric brain tumors [Metabolism, Transport, and Pharmacogenetics]
ASPET
OCTOBER 12, 2023
With this in mind, a major challenge in developing therapies for central nervous system (CNS) tumors is to overcome barriers to delivery, including the blood-brain barrier (BBB). Achieving adequate exposure of a therapeutic agent at the target is a critical determinant of efficacious chemotherapy.
100 
Let's personalize your content