Science Daily: Pharmacology News

JULY 1, 2024

The study presents solid evidence for a prediction made over a decade ago that could be key to understanding how organic molecules, the foundation of life, were first formed here on Earth. Two samples from Mars together deliver clear evidence of the origin of Martian organic material.

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Science Daily: Pharmacology News

JUNE 20, 2024

A new study presents video evidence that at least one species of terrestrial leech can jump, behavior that scientists have debated for more than a century.

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Science Daily: Pharmacology News

MARCH 28, 2024

Young to middle-aged women who reported drinking eight or more alcoholic beverages per week--more than one per day, on average--were significantly more likely to develop coronary heart disease compared with those who drank less, finds a study presented at the American College of Cardiology's Annual Scientific Session.

Disease 140

Disease 140

Science Daily: Pharmacology News

JULY 2, 2024

When experimentally testing the effectiveness of these 'treatments,' not only did they aid in recovery, but the research team found the ants' choice of care catered to the type of injury presented to them.

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Treatment Research 137

Science Daily: Pharmacology News

SEPTEMBER 27, 2024

The research shows that this species narrowly escaped extinction by hunting, resulting in lasting genetic effects in the present population. A new international study has revealed the genetic impact of hunting in northern elephant seals.

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International Research 127

BioPharma Drive: Drug Pricing

MAY 3, 2024

Newly disclosed Phase 3 results presented Friday match findings the biotech disclosed last year, while offering a more comprehensive look at how its drug stacks up to rival therapies.

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Drugs Therapies 125

BioPharma Drive: Drug Pricing

OCTOBER 31, 2024

In an investor presentation, executives hinted at the possibility of seeking an accelerated approval of trontinemab if it can significantly lower levels of amyloid in a Phase 3 trial.

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Trials Drugs 124

Chemical Biology and Drug Design

AUGUST 10, 2023

This 32CA, which takes place through a non-concerted one-step mechanism, presents a total ortho regio- and endo stereoselectivity, which is controlled by the formation of two intramolecular H … O hydrogen bonds. The high nucleophilic character of AY 10, N  = 4.39 eV, eV, allows explaining that the most favorable TS-on is 13.9 kcal mol

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Drugs Research 190

Science Daily: Pharmacology News

MAY 15, 2024

Scientists discover the cells and hormones that inspire mice to nurture their young; the same hormones are also present in humans. The answer may be a previously unknown hormone-generating cell.

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Science Daily: Pharmacology News

AUGUST 16, 2024

Previous scientific studies have indicated that North American dog lineages were replaced with European ones between 1492 and the present day. To better understand the timing of this replacement, researchers sequenced mitochondrial DNA from archaeological dogs.

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DNA Research 129

Science Daily: Pharmacology News

SEPTEMBER 19, 2024

A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).

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Marketing Virus Disease 135

Chemical Biology and Drug Design

SEPTEMBER 20, 2023

In the presented manuscript, we investigated the effect of the TRAIL-gene, transfected by an innovative bioinspired lipid vector BSV163/DOPE in the presence or absence of cisplatin, to fight against sensitive and resistant ovarian cancer. Abstract Ovarian cancer is the seventh most frequently diagnosed cancer among women worldwide.

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Treatment Disease Research 190

Chemical Biology and Drug Design

DECEMBER 15, 2023

Due to the complex pathological processes underlying neurodegeneration, at present, there is no viable therapy available for neurodegenerative disorders. Abstract Neurodegenerative disorders, which affect millions worldwide, are marked by a steady decline of neurons that are selectively susceptible.

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Disease Therapies Treatment Research 189

Science Daily: Pharmacology News

APRIL 30, 2024

Researchers have developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores that, when exposed to nutrients present in compost, germinate and break down the material at the end of its life cycle. A new type of bioplastic could help reduce the plastic industry's environmental footprint.

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Research 125

BioPharma Drive: Drug Pricing

JUNE 8, 2023

Moderna presented new data at ASCO for its melanoma shot, highlighting progress with a personalized approach that’s also being pursued by BioNTech and Gritstone.

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Vaccine 132

Science Daily: Pharmacology News

MARCH 21, 2024

The new find is the astronomical equivalent of archeologists identifying traces of an initial settlement that grew into a large present-day city.

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ASPET

JUNE 4, 2024

The goal of the present study was to determine the antiarthritic potential of the minor cannabinoid 8 -THC using the collagen-induced arthritis (CIA) mouse model. Adult male DBA/1J mice were immunized and boosted 21 days later with an emulsion of collagen and complete Freund's adjuvant.

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Treatment Disease Production 186

Science Daily: Pharmacology News

OCTOBER 1, 2024

Using a sophisticated brain-imaging system, neuroscientists say they have successfully reactivated a specific memory circuit in mice, causing them to seek out shelter when no shelter is actually present.

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Science Daily: Pharmacology News

APRIL 29, 2024

A new study challenges this notion by presenting compelling isotopic evidence of a strong preference for plants among 15,000-year-old hunter-gatherers from Morocco. However, due to the scarcity of well-preserved human remains from Paleolithic sites, little information exists about the dietary habits of pre-agricultural human groups.

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Science Daily: Pharmacology News

AUGUST 13, 2024

The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.

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Drugs.com

NOVEMBER 22, 2024

In the present study, approximately 10 years after 48 months of. FRIDAY, Nov. 22, 2024 -- Four years of hormone replacement therapy to help women deal with menopausal symptoms causes no harm to the brain, even over the long term, new research shows."In

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Therapies Research 107

Drug Target Review

JANUARY 15, 2024

An important limitation of antibodies against tumour antigens is that these agents direct responses to molecular targets present on the surface of the cell. Figure 1: HLA Class I presentation of peptides derived from intracellular antigens. As described below, it also presents challenges and opportunities for TCR-based therapeutics.

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Engineering DNA Virus Immune Response 110

Science Daily: Pharmacology News

OCTOBER 17, 2024

The work presents a method for manipulating the photonic states of light in a never-before-seen way, offering greater control over the evolution of photon propagation. This control makes it possible to improve the detection and number of photon coincidences, as well as the efficiency of the system.

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Research 129

Science Daily: Pharmacology News

MARCH 11, 2024

The puzzle, called the 'Hubble Tension,' is that the current rate of the expansion of the universe is faster than what astronomers expect it to be, based on the universe's initial conditions and our present understanding of the universe's evolution.

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Science Daily: Pharmacology News

FEBRUARY 29, 2024

Researchers report that the Golgi ribbon, an organelle structure previously thought to be exclusive to vertebrates, is also present in animal taxa, including mollusks, earthworms, and sea urchins.

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Research 126

Antidote

MARCH 12, 2024

For many people, participating in a research study presents an interesting opportunity with many benefits to volunteering. While there are many types of clinical research, all with distinct goals and timelines, trial volunteers will follow a similar path when taking part. Read on to learn more about the process.

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Trials Research Clinical Research 119

Drugs.com

SEPTEMBER 11, 2024

11, 2024 -- The weight-loss drug liraglutide helped obese children lower their BMI and reach a healthier weight, researchers report.The findings, published Tuesday in the New England Journal of Medicine and presented. WEDNESDAY, Sept.

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Research Drugs 116

Science Daily: Pharmacology News

JUNE 13, 2024

The work presents a simple approach to create complex nanostructures through a technique called self-assembly. Researchers have engineered nanosized cubes that spontaneously form a two-dimensional checkerboard pattern when dropped on the surface of water.

Engineering 116

Engineering Research 116

Science Daily: Pharmacology News

JUNE 14, 2024

New research has found that sharks retained high levels of functional diversity for most of the last 66 million years, before steadily declining over the last 10 million years to its lowest value in the present day.

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Research 115

Science Daily: Pharmacology News

OCTOBER 21, 2024

A new modeling study shows that the El Nino event, a huge blob of warm ocean water in the tropical Pacific Ocean that can change rainfall patterns around the globe, was present at least 250 million years in the past, and was often of greater magnitude than the oscillations we see today.

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Science Daily: Pharmacology News

OCTOBER 7, 2024

Dubbed REBELS-25, this disc galaxy seems as orderly as present-day galaxies, but we see it as it was when the Universe was only 700 million years old. Researchers have discovered the most distant Milky-Way-like galaxy yet observed.

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Research 120

Science Daily: Pharmacology News

FEBRUARY 13, 2024

Since language is not required for this behavior, similar kinds of playful teasing might be present in non-human animals. Babies playfully tease others as young as eight months of age. Now cognitive biologists and primatologists have documented playful teasing in four species of great apes.

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Drug Discovery Today

OCTOBER 12, 2023

Lab industry exhibition set to host talks by a renowned TV presenter and an industry leading sustainability championLondon, 20/09/2023: The UK’s largest annual trade show for the entire lab industry, Lab Innovations has announced its keynote speakers for this year's exhibition will be TV presenter Maggie Philbin and sustainability researcher Dr Rosa (..)

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Research 113

Science Daily: Pharmacology News

DECEMBER 14, 2023

However, this protective effect is lost when only single species of gut bacteria are present. New study demonstrates that diverse communities of resident bacteria can protect the human gut from disease-causing microorganisms.

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Disease Research 127

Drugs.com

OCTOBER 28, 2024

But some patients can present with what's known as an anaplastic thyroid carcinoma (ATC) -- a rare and very aggressive tumor with a very poor prognosis. MONDAY, Oct. 28, 2024 -- Most thyroid cancers are slow-moving and, if caught early, curable.

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BioPharma Drive: Drug Pricing

SEPTEMBER 13, 2024

During an investor presentation Thursday, executives admitted to being overly optimistic their vaccine could wrest significant market share away from GSK's and Pfizer's products this year.

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Vaccine Production Marketing 111

Drugs.com

FEBRUARY 16, 2024

16, 2024 -- A little-known pesticide is likely present in the bodies of most U.S. FRIDAY, Feb. residents, raising concerns of potential reproductive and developmental problems, researchers report.In the study, the pesticide chlormequat was found in.

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Research 111