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Long-term treatment with the streptococcal exotoxin streptolysin O inhibits vascular smooth muscle contraction by inducing iNOS expression in endothelial cells [Cardiovascular]

ASPET

We previously reported that short-term treatment with SLO at relatively high concentrations (10-1000 ng/mL) diminished acetylcholine-induced, endothelial-dependent relaxation in a concentration-dependent manner. In this study, treatment of rat aorta with endothelium with SLO (0.1-10 In vivo SLO treatment (46.8

Treatment 100
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Teva Presents Real-World

The Pharma Data

Teva Presents Real-World Data for AUSTEDO® (deutetrabenazine) Tablets with 4-Week Patient Titration Kit at Psych Congress Elevate 2023 Teva Pharmaceuticals, a U.S. NYSE and TASE: TEVA),today announced 12 presentations across its neuroscience portfolio featured at the Psych Congress Elevate 2023 Annual Meeting taking place on June 1-4, 2023.

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Personalized dosing in prostate cancer treatment improves patient outcomes

SCIENMAG: Medicine & Health

CDT, Tuesday, June 27, 2023)—By monitoring early-response biomarkers in men undergoing 177Lu-PSMA prostate cancer treatment, physicians can personalize dosing intervals, significantly improving patient outcomes.

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Ninth Circuit Upholds FDA’s Authority to Regulate Stem Cell Clinic Treatments

FDA Law Blog: Biosimilars

California Stem Cell Treatment Center, Inc., At the clinics, Defendants offer treatments that consist of extracting fat tissue from patients and, through a multi-step process, turning that tissue into a liquefied mixture of stem cells, other cells and cell debris known as Stromal Vascular Fraction (SVF). By Steven J. 21 U.S.C. §

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Transforming cancer treatment for greatest impact

Drug Target Review

Could you provide insights into the driving factors behind exploring novel treatments for cancer types? Additionally, in evaluating the effectiveness of our initial pipeline asset, we sought tumours suitable for intratumoural injection that present surface-accessible lesions. What aspects prompted this research direction?

Treatment 106
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Could natural terpenes be an alternative for the treatment of neglected tropical diseases?

Chemical Biology and Drug Design

Abstract Existing chemotherapy for neglected tropical diseases (NTDs) can often be toxic and ineffective, highlighting the necessity for new treatments. Their use in combination therapy decreases the concentration of the reference drug used. Terpenes are secondary metabolites with pharmacological potential.

Treatment 100
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A combined PET-MRI scan could improve treatment for patients with early breast cancer

SCIENMAG: Medicine & Health

Milan, Italy: Using a combined scanning technique on patients with early-stage breast cancer improved treatment in almost three out of ten cases in a trial presented at the 14th European Breast Cancer Conference today (Thursday). [1]