Long-term treatment with the streptococcal exotoxin streptolysin O inhibits vascular smooth muscle contraction by inducing iNOS expression in endothelial cells [Cardiovascular]
ASPET
JUNE 10, 2024
We previously reported that short-term treatment with SLO at relatively high concentrations (10-1000 ng/mL) diminished acetylcholine-induced, endothelial-dependent relaxation in a concentration-dependent manner. In this study, treatment of rat aorta with endothelium with SLO (0.1-10 In vivo SLO treatment (46.8
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