Metabolism of macrocyclic drugs
Metabolite Tales Blog
JULY 5, 2023
Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry. [link] [3] Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles. Balazs et al.,
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