Drug Target Review

APRIL 5, 2024

Together, these attributes provide a strong foundation for protein expression with enough adaptability to produce much of the commercial and therapeutic protein market. They’re prepared for complexity Successful expression of the gene of interest is not sufficient on its own for large-scale production.

Protein Production 96

Protein Production Protein Expression Bioinformatics Production 96

Drug Discovery World

NOVEMBER 8, 2023

Cell line and systems engineering The sixth track of PEGS Europe 2023 is Cell Line and Systems Engineering, which will feature a range of sessions made up of presentations, talks and posters which cover applying data science to enhance protein expression, and engineering and developing host cell lines. Claes Gustafsson, Ph.D,

Engineering 162

Engineering Protein Expression Therapies Science 162

Drug Discovery World

NOVEMBER 30, 2023

This presentation covered three primary drivers for a protein expression model: speed, cost and sustainability. “It

Protein Expression 147

Protein Expression Engineering DNA Therapies 147

Drug Discovery World

APRIL 30, 2024

This is essential to its use as a therapeutic agent and gives the technology a vast versatility making it suitable to treating a wide range of diseases – especially those that have high protein expression. mRNA-based approaches can produce proteins / peptides by using protein synthesis which is processed in a transfected cell 1.

Therapies 130

Therapies RNA Vaccine Small Molecule 130

Drug Discovery World

NOVEMBER 9, 2023

Thereafter, there will be the following presentations: Georgios Skretas, PhD, Director, Institute for Bio-innovation, Biomedical Sciences Research Center “Alexander Fleming;” Founder & CEO, ResQ Biotech, on: ‘Development of specialised bacterial strains for high-level production of recombinant membrane proteins’.

Engineering 130

Engineering Protein Production Therapies Science 130

Drug Discovery World

NOVEMBER 13, 2023

Sandeep Talapatra, PhD, Leader Protein Science, Protein Cell & Structural Sciences, GSK, on: ‘Enhancing success rates and throughput of protein purification for drug discovery: A medium-scale approach’. These topics include: High-throughput (HTP) protein production and AI and automation in bioprocess development.

Engineering 147

Engineering Science Bioinformatics Vaccine 147

The Pharma Data

DECEMBER 3, 2020

protein expression by leveraging the non-mutant (wild-type) copy of the SCN1A gene to restore physiological Na V 1.1 These diseases, in which loss of approximately 50% of normal protein expression causes disease, are called autosomal dominant haploinsufficiencies. .–( BUSINESS WIRE )– Stoke Therapeutics , Inc.

Protein Expression 52

Protein Expression Clinical Trials Pharmacokinetics Trials 52

Drug Target Review

JULY 5, 2023

A good introduction to the use of CHO cells for biotherapeutics production can be found in an article commemorating the 20th anniversary of the approval of a product produced using CHO cells. 1 Another critical component in this first step is the selectable marker that will be inserted into the genome along with the GOIs.

Engineering 105

Engineering DNA Laboratories Production 105

The Pharma Data

JANUARY 13, 2021

The project aims to develop novel protein expression systems by leveraging recent advances in direct cell reprogramming to help improve the production of proteins which are not produced sufficiently well in existing expression systems. Mogrify – U.K.-based

Licensing 52

Licensing Licensing Clinical Trials Vaccine 52