Chemical Biology and Drug Design

AUGUST 23, 2023

We hypothesized that ligustrazine could protect liver by decreasing the inflammation response, protein production, and apoptosis in THS rats. The protein expressions were detected via western blot. Ligustrazine at doses of 100 and 1000 μg/mL was administrated in Kupffer cells isolated from THS rats.

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Protein Expression Protein Production Treatment Production 100

Broad Institute

AUGUST 24, 2022

Louis have identified biological markers in triple negative breast cancer (TNBC) that are associated with resistance to chemotherapy treatment. It is imperative that we develop approaches to predict response so that only effective treatments are given. 33, was associated with resistance to chemotherapy treatment.

DNA 52

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The Pharma Data

DECEMBER 3, 2020

New preclinical data provide additional evidence of the potential for TANGO antisense oligonucleotides (ASOs) to provide a gene-specific, disease-modifying treatment for Dravet syndrome. In this study, treatment with a TANGO ASO restored Dravet syndrome mouse PV interneuron firing frequency to that of wild-type mice. Lori Isom, Ph.D.,

Clinical Trials 52

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The Pharma Data

JANUARY 13, 2021

Food and Drug Administration gave it the green light to initiate a Phase III study of tesamorelin for the treatment of adults with Nonalcoholic Steatohepatitis (NASH) with liver fibrosis. Elsewhere across the globe: Theratechnologies – In a full-year fiscal report, Montreal-based Theratechnologies Inc. This week, the company said the U.S.

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