Protein Production Research Small Molecule 
Drug Target Review
NOVEMBER 1, 2023
Could you provide an overview of your research on target directed cancer drug discovery, particularly your focus on protein lagging interactions. I work in the Centre for Cancer Drug Discovery (CCDD) at The Institute of Cancer Research in London, which is an academic drug discovery centre. Acta Cryst. Acta Cryst.
Dark Matter Blog
JULY 16, 2021
Growing up in Shrewsbury, Massachusetts, it was natural for me to attempt to get a summer job up the road at the Worcester Foundation for Biomedical Research, where the first oral contraceptive was created. I am now at the end of a career that has comprised nearly 10 years of academic research and 35 years in biotechnology.
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The Pharma Data
MARCH 23, 2022
To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase. Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. The researchers discovered that Ebola virus polymerase hijacks a cellular protein called GSPT1.
The Pharma Data
OCTOBER 14, 2020
Premature stop codons are point mutations that disrupt protein synthesis from messenger RNA. As a consequence, patients with premature stop codon diseases have reduced or eliminated protein production from the mutation bearing allele accounting for some of the most severe phenotypes in these genetic diseases.
Codon
MARCH 20, 2023
The molecular grammar of protein disorder guiding genome-binding locations. Nucleic Acids Research. Point-of-care peptide hormone production enabled by cell-free protein synthesis. Marine biofilm engineered to produce current in response to small molecules. Nucleic Acids Research. Krypotou E.
PLOS: DNA Science
AUGUST 8, 2024
Imprinting disorders can also result from differences between parental genders in gene expression – that is, protein production from the encoded information. The researchers scrutinized a “chemogenetic library ,” which is a collection of chemical compounds that bind to specific DNA sequences.
Codon
MAY 30, 2023
Codon Digest is my weekly roundup of research, news, and industry highlights about engineered biology. An engineered version of this protein can convert DNA bases with efficiencies up to 92%. Researchers introduced between 5 and 11 mutations in the PLD enzyme to make a series of superPLD variants. Nucleic Acids Research.
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