Remove Protein Production Remove Therapies Remove Virus
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Gene editing extends lifespan in mouse model of prion disease

Broad Institute

His lab had just developed base editing, a gene-editing approach that makes single-letter changes in DNA and can shut down protein production using strategies including installing a stop signal in the genetic code. They then administered the AAVs to mice infected with the human prion protein. Nature Medicine.

Disease 144
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Messenger RNAs with multiple “tails” could lead to more effective therapeutics

Broad Institute

Messenger RNAs with multiple “tails” could lead to more effective therapeutics By Corie Lok March 22, 2024 Breadcrumb Home Messenger RNAs with multiple “tails” could lead to more effective therapeutics Scientists have engineered long lasting mRNAs that increased therapeutic protein production in cells and animals.

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Targeting a human protein may stop Ebola virus in its tracks

The Pharma Data

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase. Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. Drugs that target polymerase could potentially treat Ebola virus infections and save lives.

Virus 52
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Codon Digest: Bacteria Resist Every Virus

Codon

Signal Transduction and Targeted Therapy. Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast. Optogenetic closed-loop feedback control of the unfolded protein response optimizes protein production. Molecular Therapy. Gene Therapy. Szymczak P. Karlikow M.

Virus 52
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Series A Financing of 570 Million Yen Procured by Epsilon Molecular Engineering: A Next-Generation Medium Sized Molecular Biotechnology-Based Drug Discovery Firm

The Pharma Data

Using the obtained sequencing data, Kao Corporation was able to produce an antibody sample in one week using protein production technology such as enzymes cultivated by our technology. Comment from Fumiharu Muroga, Growth Manager at Real Tech Fund] “Proteins are an important structural component of living things.

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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. 3/ Cell Membrane Editor A cell is a lipid shell with lots of DNA, proteins, and RNA molecules inside. Read *An engineered influenza virus to deliver antigens for lung cancer vaccination.

DNA 52
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. 3/ Cell Membrane Editor A cell is a lipid shell with lots of DNA, proteins, and RNA molecules inside. Read *An engineered influenza virus to deliver antigens for lung cancer vaccination.

DNA 52