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His lab had just developed base editing, a gene-editing approach that makes single-letter changes in DNA and can shut down proteinproduction using strategies including installing a stop signal in the genetic code. They then administered the AAVs to mice infected with the human prion protein. Nature Medicine.
Messenger RNAs with multiple “tails” could lead to more effective therapeutics By Corie Lok March 22, 2024 Breadcrumb Home Messenger RNAs with multiple “tails” could lead to more effective therapeutics Scientists have engineered long lasting mRNAs that increased therapeutic proteinproduction in cells and animals.
To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase. Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. Drugs that target polymerase could potentially treat Ebola virus infections and save lives.
Signal Transduction and Targeted Therapy. Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast. Optogenetic closed-loop feedback control of the unfolded protein response optimizes proteinproduction. Molecular Therapy. Gene Therapy. Szymczak P. Karlikow M.
Using the obtained sequencing data, Kao Corporation was able to produce an antibody sample in one week using proteinproduction technology such as enzymes cultivated by our technology. Comment from Fumiharu Muroga, Growth Manager at Real Tech Fund]
“Proteins are an important structural component of living things.
This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. 3/ Cell Membrane Editor A cell is a lipid shell with lots of DNA, proteins, and RNA molecules inside. Read *An engineered influenza virus to deliver antigens for lung cancer vaccination.
This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. 3/ Cell Membrane Editor A cell is a lipid shell with lots of DNA, proteins, and RNA molecules inside. Read *An engineered influenza virus to deliver antigens for lung cancer vaccination.
Germany-based Cevec Pharmaceuticals GmbH signed a licensing agreement with Biogen for the use of its proprietary ELEVECTA Technology for the manufacturing of adeno-associated virus (AAV) vectors for gene therapy applications. The deal will provide Biogen the rights to use the technology across their portfolio of gene therapyproducts.
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