Remove Protein Production Remove Vaccine Remove Virus
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Codon Digest: Bacteria Resist Every Virus

Codon

Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast. Optogenetic closed-loop feedback control of the unfolded protein response optimizes protein production. How cell-free processes could speed up vaccine development. How to build a virus-proof cell.

Virus 52
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Messenger RNAs with multiple “tails” could lead to more effective therapeutics

Broad Institute

Messenger RNAs with multiple “tails” could lead to more effective therapeutics By Corie Lok March 22, 2024 Breadcrumb Home Messenger RNAs with multiple “tails” could lead to more effective therapeutics Scientists have engineered long lasting mRNAs that increased therapeutic protein production in cells and animals.

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Merkin Prize in Biomedical Technology awarded to F. William Studier for development of widely used protein- and RNA-production platform

Broad Institute

His T7 expression technology can be used to make large quantities of nearly any RNA or protein and has been for decades, and continues to be, a mainstay of biomedical research and pharmaceutical production. In 2020, scientists used the T7 platform to produce enough mRNA for COVID-19 vaccines to vaccinate millions of people in the U.S.

RNA 84
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Elasmogen announces a panel of novel, potent, anti-COVID-19 therapeutic candidates identified through collaboration with U.S. research partners

The Pharma Data

The newly identified anti-COVID-19 Spike protein VNARs block infection of the virus (in live viral assays) at doses as low as 200 pM, equivalent to the best reported antibodies and much better than many. It is therefore vital that we continue with drug discovery approaches in parallel with the global vaccination role out.”

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BioSpace Global Roundup: Cevec Licenses AAV Program to Biogen

The Pharma Data

Germany-based Cevec Pharmaceuticals GmbH signed a licensing agreement with Biogen for the use of its proprietary ELEVECTA Technology for the manufacturing of adeno-associated virus (AAV) vectors for gene therapy applications. The deal will provide Biogen the rights to use the technology across their portfolio of gene therapy products.

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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

Read *An engineered influenza virus to deliver antigens for lung cancer vaccination. Read Meningococcal ACWYX conjugate vaccine in 2-to-29-year-olds in Mali and Gambia. Read A non-transmissible live attenuated SARS-CoV-2 vaccine. million children have received this vaccine so far, and the rollout is far from simple.

DNA 52
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

Read *An engineered influenza virus to deliver antigens for lung cancer vaccination. Read Meningococcal ACWYX conjugate vaccine in 2-to-29-year-olds in Mali and Gambia. Read A non-transmissible live attenuated SARS-CoV-2 vaccine. million children have received this vaccine so far, and the rollout is far from simple.

DNA 52