Conversations in Drug Development Trends

DECEMBER 12, 2022

What is the difference between a Clinical Laboratory Improvement Amendments (CLIA)-approved laboratory vs a research laboratory? The Centers for Medicare & Medicaid Services (CMS) regulates all clinical laboratory testing performed on human samples in the US through CLIA.

Clinical Trials 52

Clinical Trials Trials Laboratories Research Laboratories 52

The Pharma Data

JANUARY 21, 2021

The findings from the National Institutes of Health-supported prevention study, which enrolled nearly 1,100 participants, are significant given that until now a monoclonal antibody had not been shown to help prevent infection from COVID-19 in a late-stage trial.

Nurses 52

Nurses Research Laboratories Laboratories Virus 52

The Pharma Data

SEPTEMBER 21, 2020

“These new data from our LEAP clinical program show encouraging activity across several aggressive cancer types and expand our knowledge about the potential of KEYTRUDA plus LENVIMA to help a range of patients with these cancers,” said Scot Ebbinghaus, vice president, Clinical Research, Merck Research Laboratories.

Research Laboratories 52

Research Laboratories Laboratories Trials Therapies 52

Codon

OCTOBER 3, 2023

.” Can a bit of money, combined with lots of time and thoughtful community-building, foster an entire generation of writers who seed ideas, push scientific fields in new directions, or build the companies, non-profits, and research laboratories that will lead us into the future? We think so.

Research Laboratories 86

Research Laboratories Science Laboratories International 86

Broad Institute

OCTOBER 17, 2023

That interest in science led her to a weekend science course and a field trip to a plant research laboratory, where she saw scientists hybridizing roses and genetically modifying tomatoes. As she drew arrows connecting the evaporation, condensation, and precipitation phases, she thought, “This makes sense to me.

Research 98

Research Small Molecule Science Disease 98

The Strateos Blog: Drug Discovery

DECEMBER 13, 2021

AUTOMATION CAN OVERCOME BOTTLENECKS IN SYNTHETIC BIOLOGY PIPELINES Daniels’ talk entitled Accelerating Riboswitch Engineering for the Development of Human Performance Biosensors outlines a recent client collaboration with the Air Force Research Laboratory (AFRL) where Strateos’ automated cloud lab was leveraged to accelerate rational (..)

Engineering 52

Engineering Protein Expression Research Laboratories RNA 52

The Connected Lab

APRIL 29, 2020

When time is critical to the success of your laboratory’s mission, you need proven solutions that connect seamlessly and support your end-to-end workflow.

Laboratories 52

Laboratories Vaccine Research Laboratories Treatment 52

PerkinElmer

MAY 28, 2020

The handling of these pathogens needs to take place in research laboratories that are designated as biosafety level 3 or higher due to its dangerous infectious nature. Unfortunately, the road towards treatment can be time-consuming, especially when utilizing assays with live virus.

Vaccine 52

Vaccine Disease Virus Small Molecule 52

The Pharma Data

NOVEMBER 19, 2020

Patel currently serves as the director of Infectious Diseases Research Laboratory at the Mayo Clinic, as well as co-director of the clinical Bacteriology Laboratory. Prior to FDNA, Gelbman served as a corporate and transactional attorney in Israel as well as the United States.

Laboratories 52

Laboratories Research Laboratories Science Organic Chemistry 52

The Pharma Data

AUGUST 31, 2021

“While the treatment landscape has evolved, an unmet need remains for appropriate patients newly diagnosed with certain types of advanced urothelial carcinoma who are not eligible for platinum-containing chemotherapy,” said Dr. Scot Ebbinghaus, vice president, clinical research, Merck Research Laboratories. “We

FDA Approval 52

FDA Approval Treatment FDA Research Laboratories 52

The Pharma Data

JULY 29, 2021

About Loxo Oncology at Lilly Loxo Oncology at Lilly was created in December 2019, combining the Lilly Research Laboratories oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. For more information, please visit www.kumquatbiosciences.com.

Small Molecule 52

Small Molecule Immune Response Research Laboratories Laboratories 52

The Pharma Data

JANUARY 26, 2021

“These exciting results, which replicate positive phase 2 data in a much larger set of patients, add valuable clinical evidence about the role neutralizing antibodies can play in fighting this pandemic,” said Daniel Skovronsky, Eli Lilly’s chief scientific officer and president of Lilly Research Laboratories.

Vaccine 52

Vaccine Virus Research Laboratories Trials 52

Drug Target Review

NOVEMBER 1, 2023

Another key difference with industry is the close partnership with the Royal Marsden Hospital, the first hospital in the world dedicated to cancer diagnosis, treatment, research and education. Both of the ICR’s research laboratory sites in Sutton and in Chelsea are in close proximity to the Royal Marsden Hospital sites.

Fragment Screening 96

Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96

KIF1A

MAY 24, 2023

A New Opportunity: the KIF1A Research Network in Action KIF1A.ORG was presented with such an opportunity by teaming up with Dr. Rebecca Shi of Stanford University, who worked to create a research laboratory course for undergraduates in the Stanford Biology department for the Spring 2023 semester.

Disease 98

Disease Laboratories Research Science 98

The Pharma Data

OCTOBER 12, 2021

The winning research receives 5,000 USD and a bronze horse for the research that has the highest translational potential; the investigator is awarded with 1,000 USD and the research laboratory 4,000 USD to continue the great work. This year, Prof.

Research Laboratories 52

Research Laboratories Laboratories Therapies Production 52

The Pharma Data

JANUARY 4, 2021

” This method may also provide significant cost-savings, particularly in relation to antibiotic-driven selection in research laboratories. Justin is replacing that with the gene for these fluoride exporters.”

Engineering 52

Engineering DNA Laboratories Research Laboratories 52

Codon

JULY 17, 2024

In a quiet New York town, an amateur scientist has constructed a fully equipped research laboratory in which to advance plant biology research. ” Earlier this year, we sent a photographer to Sebastian’s home laboratory. Sebastian Cocioba wears the word “amateur” as a badge of honor.

Laboratories 97

Laboratories Engineering Molecular Biology Science 97

The Pharma Data

MARCH 16, 2021

The Lieber Institute for Brain Development/Maltz Research Laboratories was established in 2010 to plot a new course in biomedical research that would improve the lives of individuals affected with developmental brain disorders. The Lieber Institute for Brain Development.

Licensing 52

Licensing Licensing Research Laboratories Treatment 52

The Pharma Data

JANUARY 26, 2021

Daniel Skovronsky, Lilly’s chief scientific officer and president of Lilly Research Laboratories, said the emergence of new variants of the virus calls for new strategies even while vaccination is ongoing in many parts of the world.

Virus 52

Virus Trials Nurses Research Laboratories 52

Codon

OCTOBER 3, 2023

.” Can a bit of money, combined with lots of time and thoughtful community-building, foster an entire generation of writers who seed ideas, push scientific fields in new directions, or build the companies, non-profits, and research laboratories that will lead us into the future? We think so.

Research Laboratories 52

Research Laboratories Science Laboratories International 52

The Pharma Data

AUGUST 7, 2020

These manufactured antibodies have been developed and manufactured by Eli Lilly and Company ’s Lilly Research Laboratories in a partnership with AbCellera. The LY-CoV555 antibodies are infection fighting that can bind to the surface of viruses and prevent the virus infecting cells.

Clinical Trials 52

Clinical Trials Trials Packaging Therapies 52

Codon

DECEMBER 10, 2023

If you have protein libraries in your research laboratory, please send them to us (datasets@alignbio.org) for analysis. The biggest challenge will be to acquire DNA that encodes millions of different proteins. Synthesizing that much DNA is cost-prohibitive. We’ll analyze the proteins and provide you with expression data for free.

Protein Expression 99

Protein Expression DNA Laboratories Engineering 99

The Pharma Data

SEPTEMBER 7, 2021

“In China, esophageal and gastroesophageal junction cancers are leading causes of death, and there have been few treatment advances for patients over the past several decades,” said Dr. Scot Ebbinghaus, vice president, clinical research, Merck Research Laboratories.

Treatment 52

Treatment Research Laboratories Packaging Laboratories 52

The Pharma Data

AUGUST 30, 2021

“We are pleased to offer two potential new treatment options with KEYTRUDA for patients in Japan based on compelling data from our clinical trial program,” said Dr. Roy Baynes, senior vice president and head of global clinical development, chief medical officer, Merck Research Laboratories.

Treatment 52

Treatment Trials Research Laboratories Clinical Trials 52

The Pharma Data

NOVEMBER 22, 2020

“There is a real need to advance new treatment options for triple-negative breast cancer, an aggressive form of the disease,” said Roy Baynes, senior vice president and head of global clinical development, chief medical officer, Merck Research Laboratories, in July 2020. The drug was approved for that indication on November 13.

FDA 52

FDA Licensing Licensing Treatment 52

The Pharma Data

MARCH 5, 2021

Loxo Oncology at Lilly was created in December 2019, combining the Lilly Research Laboratories oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. Secondary endpoints include duration of response (DOR), overall survival (OS), safety, and pharmacokinetics (PK). About Loxo Oncology at Lilly.

Clinical Trials 52

Clinical Trials Pharmacokinetics Trials Therapies 52

The Pharma Data

JANUARY 17, 2021

Headquartered in Basingstoke, United Kingdom, Genus companies operate in over 25 countries on six continents, with research laboratories located in Madison, Wisconsin, USA.

Research Laboratories 52

Research Laboratories Regulations Production Laboratories 52

The Pharma Data

JUNE 1, 2022

Prior to Pfizer, Dr. Anderson worked at Merck Research Laboratories where she founded its prokaryotic bio-combinatorial engineering laboratory and initiated a bacterial vaccine program. She leaves Pfizer’s Vaccine R&D group stronger than ever and poised to continue to deliver innovative science.”.

Vaccine 40

Vaccine Research Laboratories Doctors 40

NIH Director's Blog: Drug Development

MARCH 11, 2014

Credit: Jane Ades, National Human Genome Research Institute, NIH Type 2 diabetes (T2D) tends to run in families, and over the last five years the application of genomic technologies has led to discovery of more than 60 specific DNA variants that contribute to risk.

DNA 52

DNA Drugs Disease Research Laboratories 52

Codon

DECEMBER 10, 2023

If you have protein libraries in your research laboratory, please send them to us (datasets@alignbio.org) for analysis. The biggest challenge will be to acquire DNA that encodes millions of different proteins. Synthesizing that much DNA is cost-prohibitive. We’ll analyze the proteins and provide you with expression data for free.

Protein Expression 76

Protein Expression DNA Laboratories Engineering 76

The Pharma Data

FEBRUARY 12, 2022

Lilly’s chief scientific and medical officer, and president of Lilly Research Laboratories. “With the emergence of variants such as Omicron, treatment options remain limited. ” The data supporting this EUA are primarily based on analyses from the Phase 2 BLAZE-4 trial (NCT04634409), treatment arms 9-14.

Treatment 40

Treatment Hospitals FDA Clinical Trials 40

The Pharma Data

DECEMBER 17, 2020

holding positions of increasing responsibility in Merck Research Laboratories before joining the company’s executive committee as CSO. Turner currently operates his own consulting firm, MJ Turner Consulting, where he counsels biotech, pharma, venture capital and investment banking firms. He spent 27 years at Merck & Co.

Small Molecule 52

Small Molecule Clinical Development Engineering Pharmaceuticals 52

The Pharma Data

MARCH 13, 2021

Lilly’s chief scientific officer and president of Lilly Research Laboratories. . “We are confident in the results of the TRAILBLAZER-ALZ study,” said Daniel Skovronsky, M.D., “This is the first late-stage study in Alzheimer’s disease to meet its primary endpoint at the primary analysis.

Disease 40

Disease Trials Treatment Medical Schools 40

Codon

JUNE 30, 2024

Chakrabarty was working at the Research & Development Center at General Electric Company in Schenectady, New York when he engineered a Pseudomonas strain to eat oil in 1972, but his interest in these microbes began nearly half a decade earlier while a postdoctoral fellow at the University of Illinois. Credit: Matt H.

DNA 100

DNA Engineering Laboratories Production 100

The Pharma Data

SEPTEMBER 17, 2020

Lilly ‘s chief scientific officer and president of Lilly Research Laboratories. . “Based on our initial clinical studies, we believe that virus neutralizing antibodies, including LY-CoV-555, could play an important role in the fight against COVID-19,” said Daniel Skovronsky , M.D.,

Therapies 52

Therapies Production Government Disease 52

Codon

JULY 21, 2024

Work towards improving animal welfare is ongoing and certainly not limited to research laboratories. Although, given how salient the plight of research animals can be to the public and U.S. Improving their lives through better breeding or handling amounts to an enormous increase in welfare over the long run.

Research 122

Research Engineering Disease Science 122

The Pharma Data

APRIL 16, 2021

Lilly’s chief scientific officer and president of Lilly Research Laboratories. . “Lilly moved quickly to make bamlanivimab alone available as a potentially lifesaving medicine at a time when Americans were hardest hit by COVID-19,” said Daniel Skovronsky, M.D.,

Treatment 52

Treatment Hospitals Long-Term Care Facilities Virus 52