NIH Director's Blog: Drug Discovery
NOVEMBER 5, 2020
Because SARS-CoV-2 is so highly infectious, basic researchers without access to specially designed biosafety facilities may be limited in their ability to study the virus. While the quantum dots may bind and enter human cells just like the virus, they can’t cause an infection. Naval Research Laboratory (Washington, D.C.)
BMG Labtech
MARCH 11, 2024
1,2 Anton Schuurs and Bauke van Weemen at the research laboratories of NV Organon, Oss, the Netherlands developed a similar technique which was also published in 1971. ELISAs played a pivotal role in the early detection of the human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS).
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The Pharma Data
MARCH 8, 2021
The companies today reported findings on one secondary objective from the Phase 2a study, showing a reduction in time (days) to negativity of infectious virus isolation in nasopharyngeal swabs from participants with symptomatic SARS-CoV-2 infection, as determined by isolation in Vero cell line culture. About Molnupiravir.
PerkinElmer
MAY 28, 2020
As viruses evolve over time, new, agile research applications need to be created to combat these evasive intruders from exploiting host cells. Unfortunately, the road towards treatment can be time-consuming, especially when utilizing assays with live virus.
The Pharma Data
JANUARY 21, 2021
Researchers randomized patients to either 4,200 mg of IV-administered bamlanivimab or placebo and saw that after eight weeks of participant follow-up, the 965 participants who tested negative for the virus at baseline saw a 57 percent lower frequency of symptomatic COVID-19 in the drug arm compared to the placebo arm.
The Pharma Data
JANUARY 26, 2021
Pre-clinical data showed the antibody can neutralize the virus by binding to an epitope on SARS-CoV-2 shared with SARS-CoV-1. As the virus continues to evolve, we, along with Lilly and GSK, share the view that we should pursue all possibilities to help end the pandemic and maximize the number of lives that can be saved.
The Pharma Data
JANUARY 26, 2021
Regeneron believes that the results could support emergency clearance of the treatment as a passive vaccine, which directly delivers antibodies into the body that combat the virus, compared to conventional vaccines that teach the immune system to make antibodies to the virus.
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