BioPharma Drive: Drug Pricing

APRIL 3, 2025

The Swiss drugmaker, which holds European rights to Elevidys, suspended three trials while researchers investigate the death of a young man who died following treatment.

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Science Daily: Pharmacology News

OCTOBER 18, 2023

Glioblastoma (GBM), an aggressive brain cancer, is notoriously resistant to treatment, with recurrent GBM associated with survival of less than 10 months.

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Drugs.com

JUNE 10, 2024

MONDAY, June 10, 2024 — Though overdose deaths continue to surge, there is no approved medication to treat methamphetamine use disorder.Now, an experimental two-drug therapy has yielded promising results, UCLA researchers report."These These findings h.

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BioPharma Drive: Drug Pricing

JULY 12, 2023

The decision to explore “strategic alternatives” comes about six weeks after the company sold its most advanced treatment to Novartis for nearly $90 million.

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Science Daily: Pharmacology News

MARCH 7, 2024

Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could achieve HIV remission, according to new research.

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Science Daily: Pharmacology News

SEPTEMBER 4, 2024

Researchers have designed, in mice, an approach to minimizing the damage from a spinal cord injury through the use of engineered immune cells. Mice given the treatment had improved recovery from injuries, demonstrating potential for developing the therapy for people.

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Science Daily: Pharmacology News

JULY 26, 2024

New therapy uses synthetic nanofibers to mimic the natural signaling of a protein that is crucial for cartilage formation and maintenance. Researchers found that intensifying the motion of molecules within the nanofibers led to more components needed for regeneration.

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Drugs.com

DECEMBER 13, 2024

13, 2024 -- The ancient Japanese practice of reiki "energy healing" might help some cancer patients deal with the pain that can come with infusion therapies, new research shows. FRIDAY, Dec. Outpatients receiving reiki during infusion reported.

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Drugs.com

OCTOBER 3, 2024

3, 2024 -- Japanese researchers have successfully used a transplant of human stem cells to close a hole in a key part of a monkey's retina. They say the achievement could pave the way for better treatment of small gaps that form in. THURSDAY, Oct.

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Drugs.com

JANUARY 22, 2024

Now, research shows that two leading modes of treatment -- antidepressants and an approach called behavioral activation. MONDAY, Jan. 22, 2024 -- Depression affects half of the 6 million Americans who struggle with debilitating heart failure.

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Broad Institute

JANUARY 14, 2025

The treatment, which uses base editing to make a single-letter change in DNA, reduced levels of the disease-causing prion protein in the brain by as much as 60 percent. A base-editing approach could also likely be a one-time treatment for all prion disease patients regardless of the genetic mutation causing their disease.

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Drug Target Review

DECEMBER 23, 2024

While these therapies hold great promise for improving cancer treatment outcomes, their development presents significant challenges, especially in achieving the optimal balance between efficacy and safety. To explore these challenges further, we spoke with Cheng Wang, a postdoctoral researcher at the University at Buffalo.

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Chemical Biology and Drug Design

JANUARY 30, 2025

The potential therapeutic efficacy of luteolin in the treatment of cervical cancer has been identified. Therefore, we aim to elucidate the mechanism of action of luteolin in the treatment of cervical cancer through a comprehensive approach that integrates metabolomics with bioinformatics.

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Science Daily: Pharmacology News

MAY 29, 2024

New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.

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FDA Law Blog: Drug Discovery

NOVEMBER 10, 2024

Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. The Natural History Studies Grants Program funds natural history studies that collect gather data on how rare diseases progress over time without treatment.

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Science Daily: Pharmacology News

FEBRUARY 2, 2024

A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.

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Drugs.com

APRIL 1, 2024

MONDAY, April 1, 2024 -- For folks who have battled alcohol dependency for years, any treatment that could curb or block alcohol cravings would be a huge advance.Now, research in mice is giving a glimmer of hope that just such a therapy might be.

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Broad Institute

FEBRUARY 26, 2025

Why brain cancer is often resistant to immunotherapy By Allessandra DiCorato February 26, 2025 Breadcrumb Home Why brain cancer is often resistant to immunotherapy Researchers find four coordinated gene expression programs in immune cells from glioma tumors, including two that could lead to immunotherapy resistance.

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Drug Target Review

DECEMBER 13, 2024

2 Unmet needs in lung cancer treatment Recent decades have seen significant advancements in lung cancer treatment, especially with the introduction of targeted therapies and immunotherapies, which have notably improved survival rates. 7 Recent clinical studies highlight promising developments in c-MET-targeting ADCs for NSCLC.

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Conversations in Drug Development Trends

OCTOBER 14, 2024

Fortunately, advances in clinical research are providing hope for better treatments and outcomes. With the support of global networks like ours at Worldwide Clinical Trials (Worldwide), autoimmune and bone health research is accelerating, providing new solutions to patients around the world.

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Broad Institute

JUNE 27, 2024

Science (2024) Related content New gene delivery vehicle shows promise for human brain gene therapy My Quest to Cure Prion Disease — Before It’s Too Late | Sonia Vallabh | TED Prion diseases lead to rapid neurodegeneration and death and are caused by misshapen versions of the prion protein in the brain. Credit: Neumann EN, Bertozzi TM, et al.

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Broad Institute

MAY 16, 2024

Gene therapy could potentially treat a range of severe genetic brain disorders, which currently have no cures and few treatment options. Since we came to the Broad we’ve been focused on the mission of enabling gene therapies for the central nervous system,” said Deverman, senior author on the study. “If

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Drug Target Review

MARCH 4, 2025

Obesity treatment is undergoing a major shift, much like the advances seen in cancer care. Phenomix Sciences , led by CEO Mark Bagnall, is using precision medicine to make treatments more targeted and effective. Phenomix Sciences, built on over a decade of clinical research at the Mayo Clinic, is disrupting this outdated approach.

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Broad Institute

NOVEMBER 2, 2023

Bayer and Broad Institute extend cancer therapy research collaboration By Corie Lok November 2, 2023 Breadcrumb Home Bayer and Broad Institute extend cancer therapy research collaboration Long-standing industry-academia collaboration has already resulted in three clinical oncology candidates.

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Drugs.com

NOVEMBER 7, 2023

7, 2023 -- Patients with osteoarthritis in their thumbs can get good long-term outcomes with orthotics and exercise therapy, and avoid surgery at the same time, new research shows. Our findings support nonsurgical treatment as the. TUESDAY, Nov.

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BioPharma Drive: Drug Pricing

JUNE 14, 2023

Researchers at study sponsor Seattle Children's have halted testing as they investigate the death and its potential link to the CAR-T treatment.

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Codon

FEBRUARY 13, 2024

Tom Ireland writes about the companies and technologies that are reimagining phage therapy. Goodsell, RCSB Protein Data Bank and Scripps Research. Soon after its publication, scientists, journalists, and investors were revisiting ‘phage therapy’ as a promising alternative to our failing antibiotics. Always free.

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Broad Institute

OCTOBER 29, 2024

Related groups Center for the Development of Therapeutics (CDoT) A team of researchers at Broad Institute of MIT and Harvard, in a long-term project that has included industry collaborators at Bayer and Trueline Therapeutics, has developed a compound called BRD-810 that holds promise as a therapeutic candidate for cancer.

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Drugs.com

DECEMBER 28, 2023

28, 2023 -- Two types of mental health treatment are equally effective in treating fibromyalgia patients, Swedish researchers report.They compared traditional cognitive behavioral therapy (CBT) to what is known as exposure-based. THURSDAY, Dec.

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BioPharma Drive: Drug Pricing

AUGUST 3, 2023

A treatment licensed from the NIH and in clinical testing for lupus is the startup’s lead program, while its founding “Treg” cell therapy research matures, according to CEO Peter Maag.

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Drug Target Review

MARCH 17, 2025

Neuropsychiatric treatment is on the verge of a major transformation. Historically, treatment options have been limited, with patients relying on daily medications that have minimal efficacy and troublesome side effects. “Zelquistinel is a positive modulator of NMDA receptors,” Donello explains.

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Drug Target Review

JANUARY 23, 2024

What innovative approaches and technologies are anticipated to reshape immuno-oncology treatments in 2024? Immuno-oncology, notably through checkpoint inhibitors, has significantly reshaped cancer treatment over the past decade.

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Drug Target Review

NOVEMBER 8, 2023

Problem w/ CTs and foundational understanding of Vittoria: can you explore the current limitations of cell therapies and the challenges faced by patients and providers? Currently, only a small percentage of cancers can be effectively treated with cell therapies, and there is little diversity in the currently approved products.

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Drug Target Review

JUNE 9, 2023

This exclusive interview with Dr Sharon Benzeno, Chief Commercial Officer, Immune Medicine at Adaptive Biotechnologies, unveils some ground-breaking research on T- cell therapy for cancer , which has seen the first TCR-based therapeutic candidate progress to clinical development, offering promising advancements in innovative cancer treatments.

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Drug Target Review

DECEMBER 20, 2024

These twins simulate how a patients condition might evolve without treatment, enabling researchers to compare the real-world effects of an experimental therapy against predicted outcomes. He was a postdoctoral researcher in mathematics at the University of Waterloo. Aaron received his Ph.D.

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PPD

NOVEMBER 11, 2024

As a result, biopharma and biotech companies working to bring their drug pipelines to the market require deep expertise from trusted partners to help deliver critical therapies for their patients. However, getting essential treatments to patients quickly and safely requires more than just technological innovation. billion in 2023 to 1.2

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Drug Target Review

NOVEMBER 17, 2023

They do not induce ‘graft versus host’ disease when transplanted for allogeneic therapy and there appears little sign of immune rejection. Peripheral blood NK cells have been used in allogeneic cancer therapies and shown to be safe. Only three of the CAR-NK studies were for the treatment of solid tumours.

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