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UK researchers discover new treatment target for atheroschlerosis

Drug Discovery World

Investigating how monocytes/macrophages contribute to the formation of these fatty plaques within arteries, the researchers have discovered that these cells can exist in different forms and there are particular macrophages which drive the development of the plaques.

Treatment 148
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Immune cells research could lead to personalised cancer treatments  

Drug Discovery World

Immune B cells could be used to develop cancer targeting immunotherapies, following new research by scientists at The Institute of Cancer Research, London, the University of Oxford and University of Cambridge.

Treatment 130
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New research highlights potential of combination cancer treatment 

Drug Discovery World

iOnctura, a clinical-stage biotech developing selective cancer therapies against targets that play critical roles in multiple tumour survival pathways, has published new research data in the peer-reviewed journal Cancer Research, that supports a strategy of combining autotaxin inhibitor IOA-289 with TGF-β pathway inhibitor IOA-359.

Treatment 130
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Research reveals promising novel treatment for osteoarthritis

Drug Discovery World

Researchers from the University of Manchester and Link Biologics have revealed preclinical data on a potential new treatment for osteoarthritis. The data is promising and whilst the research is in its early stages, it shows that Link_TSG6 has the potential to offer a new class of disease modifying drugs to treat osteoarthritis.”

Treatment 130
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Researchers discover treatment for rare muscle disease

Drug Discovery World

Israeli researchers have developed a drug that is effective in treating a rare genetic muscle disease. Other patients, some of whom are already in late stages of the disease, are awaiting treatment. The researchers estimate that there are dozens to hundreds of people that could benefit from the effective life-saving treatment.

Disease 130
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Meet the Researcher: Dr Joanne Taylor

Drug Discovery World

DDW’s Megan Thomas looks at a day in the life of Dr Joanne Taylor , Senior Vice President and Head of Discovery Research at Gain Therapeutics. MT: Can you provide a top line summary of your research? JT: Unfortunately, there are no approved disease modifying therapies for Parkinson’s disease, only symptomatic treatments.

Research 163
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Research uncovers how to target dormant breast cancer cells

Drug Discovery World

Scientists have discovered how breast cancer cells can ‘hibernate’ to avoid treatment and ‘wake up’ years later – causing a relapse that is more difficult to treat. We know that cancer will adapt and evolve to evade treatment, and this study shows how it will lie dormant to hide from treatment.

Research 265