Covalent Modifiers

FEBRUARY 1, 2024

Science 383 , eadi5798 (2024). Therefore, understanding mechanisms by which acquired mutations in BTK confer drug resistance and developing new therapies to overcome resistance are critically important. Skye Montoya et al. As such, chronic lymphocytic leukemia (CLL) and other B cell cancers are sensitive to inhibition of BTK.

Targeted Protein Degradation 173

Targeted Protein Degradation Clinical Trials Trials Science 173

Fierce BioTech

MARCH 15, 2024

It addresses CAR-T therapies, KRAS, radiopharmaceuticals, & targeted protein degradation. It addresses CAR-T therapies, KRAS, radiopharmaceuticals, & targeted protein degradation. Blue Matter Consulting Resource Type Whitepaper BlueMatterConsulting_250x190 (1) (2).png

Targeted Protein Degradation 52

Targeted Protein Degradation Marketing Therapies Science 52

Drug Target Review

JULY 23, 2024

I studied Natural Sciences at the University of Cambridge, where I was exposed to a range of disciplines from chemistry to physiology, specialising in my last year in biochemistry. Pushing the boundaries of science always opens the door to new, impactful developments, although there are always challenges along the way.

Small Molecule 116

Small Molecule Targeted Protein Degradation Science Disease 116

The Pharma Data

JULY 22, 2021

This collaboration has the potential to be transformational, as it combines our leadership in targeted protein degradation with Pfizer’s global capabilities and deep expertise in breast cancer. Arvinas and Pfizer are seeking to develop ARV-471 as the potential endocrine therapy of choice for patients and their physicians.

Targeted Protein Degradation 52

Targeted Protein Degradation Therapies Clinical Trials Treatment 52

The Pharma Data

OCTOBER 15, 2020

a leading biotechnology company developing small molecule therapeutics based on its proprietary uSMITE platform of targeted protein degradation technology, today announced that the company’s internal program to develop selective degraders that target key proteins within the TRK family has been published by the Journal of Medicinal Chemistry.

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Targeted Protein Degradation Small Molecule Science Disease 40

The Pharma Data

SEPTEMBER 15, 2020

The companies will receive priority admission or renewal for one year of lab bench space with access to core facilities at the MBC BioLabs life sciences incubator, including access to Amgen ‘s scientific experts and business leaders to help advance their scientific programs.

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Targeted Protein Degradation Molecular Biology Small Molecule Science 52

Elrig

MARCH 22, 2023

ELRIG will be partnering with EU-OPENSCREEN, Europe’s open-access infrastructure for chemical biology research; the Division of Chemistry in Life Sciences of the European Chemical Society; and AstraZeneca, who will be hosting the event in their Gothenburg R&D building. The symposium provides a unique opportunity to do that.”

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Targeted Protein Degradation Science Disease Laboratories 40