How to Get Drugs Into the Brain
Drug Hunter
AUGUST 21, 2023
Overall, only a few prodrugs for CNS disorders have even reached clinical trials , so for the most part traditional property-based drug design remains the best bet for the vast majority of programs. A) Progression of a Novartis HAT program from a screening hit to brain-penetrant leads. What is K p,uu ? Figure 18.
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