Therapies - Drug Discovery Digest

Scaling Phage Therapy

Codon

FEBRUARY 13, 2024

Tom Ireland writes about the companies and technologies that are reimagining phage therapy. Soon after its publication, scientists, journalists, and investors were revisiting ‘phage therapy’ as a promising alternative to our failing antibiotics. Read it on our website here. Illustration by David S. Fast forward to 2023.

Scaling Phage Therapy

New gene delivery vehicle shows promise for human brain gene therapy

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100x improvement in sight seen after gene therapy trial

Duchenne approval exposes FDA rift over Sarepta gene therapy

Cell and gene therapy investment, once booming, is now in a slump

FDA endorses speedy approval path for Regenxbio Duchenne gene therapy

New gene therapy for muscular dystrophy offers hope

A therapy candidate for fatal prion diseases turns off disease-causing gene

Artiva prices $167M IPO, riding optimism for autoimmune cell therapy

Gene therapy gets a turbo boost

Early Hints at a Gene Therapy Cure for Herpes

CAR-T for lupus: the ‘tip of the iceberg’ for cell therapy in autoimmune disease

Combo Therapy May Be Advance Against Liver Cancer

Pfizer hemophilia gene therapy arrives in US to uncertain future

New gene delivery vehicle shows promise for human brain gene therapy

Short-Term Hormone Therapy for Menopause Won't Harm Women's Brains

Can robots break the cell therapy bottleneck?

Hormone Therapy for Breast Cancer May Lower Dementia Risk

Bright Light Therapy May Ease Multiple Forms of Depression

Using stem cell-derived heart muscle cells to advance heart regenerative therapy

Iovance, with approval of ‘TIL’ cell therapy, readies for complex launch

FDA Warns of Rare Secondary Cancer Risk With CAR-T Therapies

Gene Therapy Improves Vision in People With Inherited Blindness

EMA recommends earlier use of Bristol Myers cell therapy for multiple myeloma

With Duchenne decision ahead, FDA’s Marks pushes for speedy gene therapy approvals

Sarepta scraps a Duchenne drug as gene therapy sales rise

Light Therapy Might Help Ease 'Dry' Form of Macular Degeneration

First-of-its-kind cell therapy approved by FDA for rare soft tissue cancer

Pfizer gene therapy for Duchenne fails to meet goals of key trial

Single-dose gene therapy is potentially life-changing for adults with hemophilia B

New Gene therapy trial shows restored hearing and speech in children born deaf, treated in both ears

Macrophage cell therapy: a new hope for chronic liver disease patients

FDA Approves Landmark Sickle Cell Gene Therapies, Casgevy and Lyfgenia

Major Women's Health Study Supports Hormone Replacement Therapy in Early Menopause

Secondary Tumors After CAR-T Cancer Therapies Are Rare: Study

Trial Confirms 'Life-Changing' Impact of Gene Therapy, Beqvez, for Hemophilia B

The Expansion of Cell Therapies in Asia-Pacific

Cell and gene therapy development moves into cardiac indications

Gene Therapy Reverses a Rare Cause of Vision Loss

Another Study Finds CRISPR Gene Therapy Fights Sickle Cell

CAR-T Therapy Won't Raise Odds for a Second Cancer, Study Finds

Risk of secondary cancers after CAR-T cell therapy low, according to large study

Stem Cell Therapy Could Be Breakthrough Against Type 1 Diabetes

Boys Treated With Gene Therapy for Rare Brain Disease Doing Well 6 Years Later

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