Codon

FEBRUARY 13, 2024

Tom Ireland writes about the companies and technologies that are reimagining phage therapy. Soon after its publication, scientists, journalists, and investors were revisiting ‘phage therapy’ as a promising alternative to our failing antibiotics. Read it on our website here. Illustration by David S. Fast forward to 2023.

Therapies 115

Therapies Virus DNA Clinical Trials 115

Drugs.com

OCTOBER 15, 2024

14, 2024 -- Gene therapy could help obese kids avoid health problems associated with excess weight, including arthritis, a new, preliminary study in mice suggests.The gene therapy prompts cells to convert inflammation-causing omega-6. TUESDAY, Oct.

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BioPharma Drive: Drug Pricing

AUGUST 29, 2024

Far fewer venture funding rounds were closed by cell and gene therapy developers over the first six months of 2024 than in prior years. Experts say there are several factors.

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Therapies 142

Broad Institute

MAY 16, 2024

Gene therapy could potentially treat a range of severe genetic brain disorders, which currently have no cures and few treatment options. Since we came to the Broad we’ve been focused on the mission of enabling gene therapies for the central nervous system,” said Deverman, senior author on the study. “If

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Therapies FDA Approval Engineering Disease 137

Drug Discovery Today

OCTOBER 2, 2024

Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer’s disease, and improve symptoms of neurodegeneration in mice.

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Therapies Disease Treatment 113

Drugs.com

JULY 16, 2024

TUESDAY, July 16, 2024 -- Hormone therapy for breast cancer might reduce a woman’s later risk of dementia and Alzheimer’s disease, a new study finds.Overall, hormone therapy is associated with a 7% lower risk of developing Alzheimer’s or a related d.

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Therapies Disease 111

BioPharma Drive: Drug Pricing

JUNE 21, 2024

Peter Marks’ decision to override the objections of agency staff and broaden use of Elevidys could have a “lasting impact” on gene therapy as well as the FDA, one analyst wrote.

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Therapies FDA 133

ASPET

APRIL 19, 2024

Despite the severe, unmet, medical need; there is no literature regarding on-demand, rapid-onset, short-duration, drug-induced, voiding therapies. This article provides in depth discussion of recent discovery and development of two candidates for on-demand voiding therapies.

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Therapies Hospitals Disease Drugs 100

Science Daily: Pharmacology News

JULY 17, 2024

A new gene therapy treatment for Duchenne muscular dystrophy (DMD) shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles.

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Therapies Treatment Disease Research 120

BioPharma Drive: Drug Pricing

JULY 18, 2024

The offering comes days after the publication of a paper showing what analysts said was early proof that “off-the-shelf” cell therapies can treat inflammatory diseases.

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Therapies Disease 129

Alta Sciences

NOVEMBER 4, 2024

Nonclinical Experts Discuss the Promise of Gene Therapy blussier Mon, 11/04/2024 - 21:08 HTML Driving Progress in Gene Therapy Altasciences is a leader in nonclinical research, including gene therapy. WATCH NOW Want to learn more? Speak with one of our experts.

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Science Daily: Pharmacology News

AUGUST 29, 2024

Gene therapy, the idea of fixing faulty genes with healthy ones, has held immense promise. For decades, scientists have dreamt of a future where genetic diseases, such as the blood clotting disorder hemophilia, could be a thing of the past. But a major hurdle has been finding a safe and efficient way to deliver those genes.

Therapies 111

Therapies Disease Research 111

Drugs.com

SEPTEMBER 6, 2024

6, 2024 -- Gene therapy may restore vision to children and adults robbed of their sight by a rare inherited condition called Leber congenital amaurosis, researchers report.The illness is caused by mutations in the GUCY2D gene, which. FRIDAY, Sept.

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Therapies Research 105

Drugs.com

MAY 15, 2024

WEDNESDAY, May 15, 2024 -- An experimental gene therapy could one day provide a first-ever cure for genital and oral herpes, researchers report.The gene therapy removed 90% or more of oral herpes infection in lab mice, and it also suppressed how.

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Therapies Research 119

Drugs.com

SEPTEMBER 26, 2024

25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows. THURSDAY, Sept. People with hemophilia B saw their bleeding episodes.

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Therapies Trials Clinical Trials Treatment 116

BioPharma Drive: Drug Pricing

SEPTEMBER 25, 2024

The financing will support a technology designed to make delivery of lentiviral gene therapies, which are typically administered through a complex process, more convenient.

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Therapies 98

Drugs.com

SEPTEMBER 18, 2024

18, 2024 -- Therapy dogs can help boost the spirits of health care workers in the same way they brighten the moods of hospital patients, a new study shows. WEDNESDAY, Sept. The furry, four-legged friends reduced emotional exhaustion and job stress.

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Nurses Therapies Doctors Hospitals 97

Drug Target Review

AUGUST 28, 2024

Once a patient develops advanced cirrhosis/end-stage liver disease there are no specific therapies to significantly avoid major decompensations and death in the next few years. Could you describe the platform of macrophage biology and cell engineering used by Resolution Therapeutics in developing their cell therapies?

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Therapies Disease Engineering Medical Schools 114

BioPharma Drive: Drug Pricing

MAY 29, 2024

A partnership between cell therapy delivery specialist Portal Biotechnologies and precision robotics maker Multiply Labs could address manufacturing hurdles, the CEOs said.

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Therapies 106

Drug Target Review

NOVEMBER 8, 2023

Problem w/ CTs and foundational understanding of Vittoria: can you explore the current limitations of cell therapies and the challenges faced by patients and providers? Currently, only a small percentage of cancers can be effectively treated with cell therapies, and there is little diversity in the currently approved products.

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Therapies Engineering Treatment Molecular Biology 116

Drug Target Review

NOVEMBER 29, 2023

Our primary focus is to design and develop RNA therapies for liver diseases. Our team of chemists then uses this information to develop novel therapies. By doing this, we get a superior understanding of which therapies will and will not work in human biology before a clinical trial.

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Therapies Disease RNA Engineering 102

Drug Target Review

JANUARY 4, 2024

What distinguishes Alder Therapeutics’ approach to regenerative cell therapy development from traditional methods, and how does it aim to reduce risks in the preclinical phase? Traditional approaches to regenerative cell therapy development are defined by several challenges. So, what makes these therapies unique?

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Therapies Small Molecule Production Disease 98

Drugs.com

MAY 6, 2024

MONDAY, May 6, 2024 -- A new combination therapy appears to boost the response rate for liver cancer patients receiving immunotherapy, according to results from a phase 2 clinical trial.The combo therapy involves bavituximab, a drug that.

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Therapies Drugs 112

Science Daily: Pharmacology News

SEPTEMBER 25, 2024

Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the new results of an international Phase III clinical trial.

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Therapies Clinical Trials International Trials 118

Broad Institute

JUNE 27, 2024

Science (2024) Related content New gene delivery vehicle shows promise for human brain gene therapy My Quest to Cure Prion Disease — Before It’s Too Late | Sonia Vallabh | TED Prion diseases lead to rapid neurodegeneration and death and are caused by misshapen versions of the prion protein in the brain. “As

Disease 142

Disease Therapies Engineering Clinical Trials 142

Drugs.com

SEPTEMBER 11, 2024

11, 2024 -- Contrary to a warning placed on labels for CART-T cancer therapies, use of these treatments does not appear to boost the odds for a secondary cancer later, a new study shows.Researchers at Memorial Sloan Kettering. WEDNESDAY, Sept.

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Therapies Treatment 111

Drugs.com

SEPTEMBER 26, 2024

25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows.People with hemophilia B saw their bleeding episodes. THURSDAY, Sept.

Therapies 98

Therapies Trials Clinical Trials Treatment 98

Drugs.com

SEPTEMBER 10, 2024

10, 2024 -- A form of psychotherapy can help women whose libidos have suffered as they go through menopause, a new study finds.Cognitive behavioral therapy significantly improved sexual desire and satisfaction in a small group of. TUESDAY, Sept.

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Therapies 98

Alta Sciences

NOVEMBER 4, 2024

[NEW VIDEO] Nonclinical Experts Discuss the Promise of Gene Therapy blussier Mon, 11/04/2024 - 21:08 HTML Driving Progress in Gene Therapy Altasciences is a leader in nonclinical research, including gene therapy. WATCH NOW Want to learn more? Speak with one of our experts. jpg Tags Preclinical Research Weight 1

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Drug Target Review

FEBRUARY 9, 2024

What key findings about stem cell behaviour, differentiation and integration within host tissues impact the development of stem cell therapies? Despite their potential, ADSC therapy faces several challenges in preclinical studies. Is there a certain disease or condition that you believe stem cell therapy holds the most promise for?

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Therapies Immune Response Clinical Trials Treatment 105

PLOS: DNA Science

MARCH 21, 2024

The Food and Drug Administration just announced approval of Lenmeldy (atidarsagene autotemcel), a gene therapy to treat the neurological condition metachromatic leukodystrophy (MLD). The history of gene therapy for MLD is compelling – DNA Science covered it for Rare Disease Day in 2021, here. She passed away in 2013.

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Therapies Clinical Trials DNA Trials 98

SCIENMAG: Medicine & Health

FEBRUARY 26, 2024

The 7th World Conference on Targeting Phage Therapy 2024, two-day event dedicated to advancing the field of phage research and therapy will be hosted at Corinthia Palace Malta on June 20-21.

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Therapies Clinical Trials Research Trials 89

Drugs.com

MAY 6, 2024

MONDAY, May 6, 2024 -- An injectable gene therapy caused measurable improvements in vision among a small group of people with inherited blindness, an early-stage clinical trial says.Researchers recruited 14 people with Leber Congenital Amaurosis.

Therapies 116

Therapies Clinical Trials Trials 116

Drugs.com

JUNE 18, 2024

TUESDAY, June 18, 2024 -- There's more good news in the battle against sickle cell disease, with another trial finding CRISPR gene-editing therapy delivering impressive results for patients.“It’s It’s encouraging that this gene-editing treatment con.

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Therapies Trials Treatment Disease 105

BioPharma Drive: Drug Pricing

SEPTEMBER 23, 2024

Regulatory and strategic challenges can delay the delivery of life-changing cell and gene therapies.

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Therapies 98

PPD

OCTOBER 17, 2024

Cell and gene therapy (CGT) studies are rapidly gaining momentum in the Asia-Pacific region, fueled by growing patient demand and a thriving ecosystem of innovation. In China, the high incidence of solid tumors is driving an urgent need for advanced therapies, spurring the push for new treatment approaches.

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Therapies Clinical Trials Clinical Research Trials 52

BioPharma Drive: Drug Pricing

APRIL 26, 2024

The Food and Drug Administration approval of Beqvez comes as other gene therapies for the bleeding condition that were approved earlier struggle to gain traction.

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Therapies Drugs 119