Science Daily: Pharmacology News

AUGUST 29, 2024

Gene therapy, the idea of fixing faulty genes with healthy ones, has held immense promise. For decades, scientists have dreamt of a future where genetic diseases, such as the blood clotting disorder hemophilia, could be a thing of the past. But a major hurdle has been finding a safe and efficient way to deliver those genes.

Therapies 306

Therapies Disease Research 306

Science Daily: Pharmacology News

JULY 17, 2024

A new gene therapy treatment for Duchenne muscular dystrophy (DMD) shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles.

Therapies 304

Therapies Treatment Disease Research 304

BioPharma Drive: Drug Pricing

JULY 18, 2024

The offering comes days after the publication of a paper showing what analysts said was early proof that “off-the-shelf” cell therapies can treat inflammatory diseases.

Therapies 326

Therapies Disease 326

Drugs.com

MAY 15, 2024

WEDNESDAY, May 15, 2024 -- An experimental gene therapy could one day provide a first-ever cure for genital and oral herpes, researchers report.The gene therapy removed 90% or more of oral herpes infection in lab mice, and it also suppressed how.

Therapies 298

Therapies Research 298

Drugs.com

MAY 6, 2024

MONDAY, May 6, 2024 -- A new combination therapy appears to boost the response rate for liver cancer patients receiving immunotherapy, according to results from a phase 2 clinical trial.The combo therapy involves bavituximab, a drug that.

Therapies 281

Therapies Drugs 281

BioPharma Drive: Drug Pricing

APRIL 26, 2024

The Food and Drug Administration approval of Beqvez comes as other gene therapies for the bleeding condition that were approved earlier struggle to gain traction.

Therapies 302

Therapies Drugs 302

BioPharma Drive: Drug Pricing

JULY 6, 2023

Five years after helping launch Allogene Therapeutics, Pfizer is backing another developer of “off-the-shelf” cell therapies in a deal that gives the drugmaker the chance to acquire a multiple myeloma treatment.

Therapies 333

Therapies Treatment 333

Drugs.com

JULY 16, 2024

TUESDAY, July 16, 2024 -- Hormone therapy for breast cancer might reduce a woman’s later risk of dementia and Alzheimer’s disease, a new study finds.Overall, hormone therapy is associated with a 7% lower risk of developing Alzheimer’s or a related d.

Therapies 278

Therapies Disease 278

Drugs.com

OCTOBER 7, 2024

7, 2024 -- Light therapy: It's long been a go-to therapy for seasonal affective disorder (SAD), a kind of depression that can beset some people when winter looms and days shorten.But new research is suggesting that time spent in front. MONDAY, Oct.

Therapies 278

Therapies Research 278

Science Daily: Pharmacology News

MAY 16, 2024

In an important step toward more effective gene therapies for brain diseases, researchers have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein.

Therapies 318

Therapies Engineering Disease Research 318

Drugs.com

MAY 6, 2024

MONDAY, May 6, 2024 -- An injectable gene therapy caused measurable improvements in vision among a small group of people with inherited blindness, an early-stage clinical trial says.Researchers recruited 14 people with Leber Congenital Amaurosis.

Therapies 290

Therapies Clinical Trials Trials 290

Science Daily: Pharmacology News

APRIL 26, 2024

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high.

Therapies 318

Therapies Research 318

BioPharma Drive: Drug Pricing

MAY 29, 2024

A partnership between cell therapy delivery specialist Portal Biotechnologies and precision robotics maker Multiply Labs could address manufacturing hurdles, the CEOs said.

Therapies 269

Therapies 269

Science Daily: Pharmacology News

JANUARY 2, 2025

This study marks an important step toward regenerative therapies to prevent heart failure. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement.

Therapies 305

Therapies Research 305

BioPharma Drive: Drug Pricing

JULY 15, 2024

The company claims the results support exploring the possibility of an accelerated approval, citing flexibility by FDA officials in reviewing rare disease gene therapies.

Therapies 296

Therapies FDA Disease 296

Drugs.com

MARCH 19, 2025

WEDNESDAY, March 19, 2025 -- A patient has died while receiving Elevidys, a gene therapy for Duchenne muscular dystrophy, marking the first known death linked to the treatment. The company behind the drug, Sarepta Therapeutics, said that the.

Therapies 249

Therapies Treatment Drugs 249

BioPharma Drive: Drug Pricing

JANUARY 23, 2024

A black box warning for secondary T cell malignancies should be added to the labeling of all six approved CAR-T therapies, the agency said.

Therapies 308

Therapies FDA 308

BioPharma Drive: Drug Pricing

JANUARY 30, 2024

Since a landmark paper in 2022, drugmakers have begun nearly a dozen trials of cell therapies for lupus, with more set to start. Here’s why their efforts are worth watching.

Therapies 353

Therapies Disease Trials 353

Drugs.com

JANUARY 6, 2025

MONDAY, Jan 6, 2025 -- Turns out, starting physical therapy earlier after a concussion may significantly improve recovery outcomes.A new study published recently in the Physical Therapy & Rehabilitation Journal followed just over 200 adults.

Therapies 264

Therapies 264

Drugs.com

OCTOBER 22, 2024

22, 2024 -- Light therapy could be a useful treatment for the most common form of age-related macular degeneration, a new study says.The therapy, called photobiomodulation or “red light” therapy, can reduce the risk of vision loss and. TUESDAY, Oct.

Therapies 264

Therapies Treatment 264

BioPharma Drive: Drug Pricing

MAY 24, 2024

But the head of the FDA’s CBER office didn’t tip where the agency stands on potentially broadening use of Sarepta’s Duchenne gene therapy Elevidys.

Therapies 297

Therapies FDA 297

Drugs.com

DECEMBER 8, 2023

Food and Drug Administration on Friday approved two milestone gene therapies for sickle cell disease, including the first treatment ever approved that uses gene-editing technology. FRIDAY, Dec. 8, 2023 -- The U.S. Casgevy, developed by Vertex.

FDA Approval 312

FDA Approval Therapies FDA Treatment 312

Drugs.com

MAY 1, 2024

WEDNESDAY, May 1, 2024 -- Hormone replacement therapy can safely ease middle-aged women’s symptoms during early menopause, data from a major women’s health study show. Women younger than 60 can use hormone replacement to treat symptoms.

Therapies 290

Therapies 290

BioPharma Drive: Drug Pricing

NOVEMBER 7, 2024

Elevidys sales have increased since the FDA made a controversial choice to expand the therapy's use. Now, Sarepta is abandoning a successor to its drug Exondys 51, citing an “evolving" treatment landscape.

Therapies 281

Therapies Drugs FDA Treatment 281

BioPharma Drive: Drug Pricing

AUGUST 2, 2024

Adaptimmune’s Tecelra is the first TCR cell therapy to reach market and, at $727,000, is also the priciest cellular medicine for cancer in the U.S.

Therapies 304

Therapies FDA Marketing 304

Science Daily: Pharmacology News

SEPTEMBER 25, 2024

Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the new results of an international Phase III clinical trial.

Therapies 300

Therapies Clinical Trials International Trials 300

Science Daily: Pharmacology News

JUNE 5, 2024

A new clinical trial of five children with inherited deafness found administering gene therapy in both ears led to restored hearing and speech, and additional gains including sound source localization, ability to hear in noisy environments, and for two children, abillity to appreciate music.

Therapies 309

Therapies Trials Clinical Trials International 309

BioPharma Drive: Drug Pricing

DECEMBER 8, 2023

Casgevy, the first CRISPR therapy approved by the FDA, will cost $2.2 million, while a competing genetic medicine also cleared Friday is priced at $3.1

Therapies 304

Therapies FDA 304

BioPharma Drive: Drug Pricing

JUNE 12, 2024

The negative results from the Phase 3 study, called Ciffreo, come a little more than a month after Pfizer said a patient died in another trial of the gene therapy.

Therapies 290

Therapies Trials 290

Drugs.com

SEPTEMBER 26, 2024

25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows. THURSDAY, Sept. People with hemophilia B saw their bleeding episodes.

Therapies 290

Therapies Trials Clinical Trials Treatment 290

Drugs.com

JUNE 13, 2024

THURSDAY, June 13, 2024 -- CAR-T cell therapy to treat blood cancers is safer than previously thought, with little risk that the immunotherapy will create secondary cancers, a new study finds.The U.S. Food and Drug Administration issued a warning.

Therapies 276

Therapies Drugs 276

Science Daily: Pharmacology News

FEBRUARY 14, 2025

One day, researchers want to use switches of this kind to trigger cell therapies for various metabolic diseases. Researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin.

Therapies 273

Therapies Disease Research 273

BioPharma Drive: Drug Pricing

MARCH 18, 2025

A young man treated with Elevidys died of acute liver failure. The case may give doctors pause before prescribing the treatment in the future, some analysts wrote.

Therapies 357

Therapies Doctors Treatment 357

Drugs.com

SEPTEMBER 6, 2024

6, 2024 -- Gene therapy may restore vision to children and adults robbed of their sight by a rare inherited condition called Leber congenital amaurosis, researchers report.The illness is caused by mutations in the GUCY2D gene, which. FRIDAY, Sept.

Therapies 264

Therapies Research 264

Drugs.com

JUNE 18, 2024

TUESDAY, June 18, 2024 -- There's more good news in the battle against sickle cell disease, with another trial finding CRISPR gene-editing therapy delivering impressive results for patients.“It’s It’s encouraging that this gene-editing treatment con.

Therapies 264

Therapies Trials Treatment Disease 264

Drugs.com

JANUARY 24, 2024

Food and Drug Administration has told drugmakers to add a boxed warning to a type of cancer treatment called CAR-T therapy, saying the treatment itself may sometimes cause a secondary. WEDNESDAY, Jan. 24, 2024 (Healthday News) -- The U.S.

Therapies 306

Therapies FDA Treatment Drugs 306

Science Daily: Pharmacology News

JANUARY 22, 2025

Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include osteoporosis, sexual dysfunction and blood clots. Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women.

Treatment 294

Treatment Therapies Drugs Research 294