Science Daily: Pharmacology News
NOVEMBER 16, 2024
The Earth's total amount of freshwater dropped abruptly starting in May 2014 and has remained low ever since. The shift could indicate Earth's continents have entered a persistently drier phase.
Nvidia Developer: Drug Discovery
NOVEMBER 13, 2024
The ability to compare the sequences of multiple related proteins is a foundational task for many life science researchers. This is often done in the form of a. The ability to compare the sequences of multiple related proteins is a foundational task for many life science researchers. This is often done in the form of a multiple sequence alignment (MSA), and the evolutionary information retrieved from these alignments can yield insights into protein structure, function, and evolutionary history.
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BioPharma Drive: Drug Pricing
NOVEMBER 6, 2024
Pioneers like Alnylam Pharmaceuticals have led the RNA interference field for years. Now, a crop of young biotechs is building on that foundation by taking the drugmaking technology in new directions.
NIOSH Science Blog: Drugs
NOVEMBER 7, 2024
Introduction No Shave November is a great opportunity to grow out your beard for a good cause. But if you rely on a tight-fitting respirator for work, that extra facial hair could pose a safety concern. Respirators protect workers from harmful particles, but their effectiveness depends on forming a tight seal against your skin. So, what does that mean for your growing beard during No Shave November?
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Codon
NOVEMBER 8, 2024
An opinion essay by Liyam Chitayat The cells within our body are the remnants of an ancient alliance. In a 1967 paper called “ On the Origin of Mitosing Cells ,” American evolutionary biologist Lynn Margulis proposed an idea that, upon first hearing, seems ludicrous. Her paper, in fact, was rejected by 12 different journals before it was published.
Antidote
NOVEMBER 20, 2024
Being a caregiver is one of the most selfless and demanding roles you can take on. Whether you're looking after a parent, spouse, child, or loved one, juggling all of the daily responsibilities that come with it can quickly feel overwhelming. With so much focus on taking care of others, it’s easy to put yourself and your needs on the back burner. While your focus is understandably on your loved one, it’s important to remember that your own well-being matters too.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
NOVEMBER 19, 2024
TUESDAY, Nov. 19, 2024 -- Women who won't leave the house without makeup or a spritz of hairspray may want to think twice about those habits when they're pregnant or breastfeeding.New research links these and other personal care products, including.
BioPharma Drive: Drug Pricing
NOVEMBER 15, 2024
At an event hosted by BioPharma Dive, drugmaker executives and investors discussed the importance of focus, smart spending and maintaining lines of sight to the clinic.
Broad Institute
NOVEMBER 6, 2024
Q&A: How a partnership between physicians and researchers aims to make cancer drugs safer By Leah Eisenstadt November 6, 2024 Breadcrumb Home Q&A: How a partnership between physicians and researchers aims to make cancer drugs safer Broad and Mass General researcher Alexandra-Chloé Villani and Mass General oncologist Kerry Reynolds describe their pioneering effort to better understand, diagnose, and manage dangerous complications from cancer immunotherapy.
FDA Law Blog: Biosimilars
NOVEMBER 11, 2024
By Deborah L. Livornese & JP Ellison — On November 8, 2024, FDA issued a proposed order to remove the oral decongestant ingredient phenylephrine (including both phenylephrine hydrochloride and phenylephrine bitartrate) (collectively, PE) from the OTC monograph on the basis of a lack of effectiveness. FDA also noted that it has concluded that no safety signal was identified for oral PE at doses permitted under the monograph.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
NOVEMBER 12, 2024
With just a cryptocurrency wallet, cybercriminals can now execute complex cyberattacks without advanced technical knowledge or sophisticated software. This alarming trend is a byproduct of the growing popularity of cloud computing and the “as-a-service” model, where services like infrastructure, recovery, and cybersecurity are now accessible on demand.
Science Daily: Pharmacology News
NOVEMBER 7, 2024
It's common knowledge that our brains -- and, specifically, our brain cells -- store memories. But a team of scientists has discovered that cells from other parts of the body also perform a memory function, opening new pathways for understanding how memory works and creating the potential to enhance learning and to treat memory-related afflictions.
Drugs.com
NOVEMBER 15, 2024
FRIDAY, Nov. 15, 2024 -- Waning vaccine coverage has fueled a 20% spike in measles cases worldwide, with 10.3 million people struck by the preventable illness in 2023, health officials reported Wednesday."Inadequate immunization coverage globally.
BioPharma Drive: Drug Pricing
NOVEMBER 11, 2024
Negative drug results cost AbbVie billions of dollars in market value and convinced analysts that Bristol Myers had placed a better bet in buying Karuna Therapeutics.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Broad Institute
NOVEMBER 6, 2024
Study reveals how cancer immunotherapy may cause heart inflammation in some patients By Leah Eisenstadt November 6, 2024 Breadcrumb Home Study reveals how cancer immunotherapy may cause heart inflammation in some patients Myocarditis is driven by a different immune response than the anti-tumor one, suggesting that the serious complication could one day be managed without halting cancer therapy.
FDA Law Blog: Biosimilars
NOVEMBER 6, 2024
By Sara W. Koblitz — The fight between Jazz, Avadel, and FDA over narcolepsy drug sodium oxybate has been a long and arduous one. Starting in 2022 with a patent certification requirement, both Jazz and Avadel have sued FDA over this drug, with Jazz most recently bringing suit challenging FDA’s decision that Avadel’s Lumryz (sodium oxybate) is clinically superior to Jazz’s Xywav (sodium oxybate) in 2023.
Perficient: Drug Development
NOVEMBER 12, 2024
Healthcare leaders are engaging us in a variety of discussions to explore intelligent automation’s role for complex business challenges, ranging from efforts to enhance consumer trust and use artificial intelligence (AI) in effective ways, to navigating change that comes with prior authorization mandates. This series shares key insights coming from those discussions.
Science Daily: Pharmacology News
NOVEMBER 13, 2024
How much land, water, and other resources does our lifestyle require? And how can we adapt this lifestyle to stay within the limits of what the Earth can give? A new article tackles these questions.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
NOVEMBER 13, 2024
WEDNESDAY, Nov. 13, 2024 -- The blockbuster GLP-1 drug semaglutide (Ozempic, Wegovy) could curb drinking for people battling alcohol use disorder, helping them to avoid crises that require hospitalization, new research shows. Numerous studies had.
BioPharma Drive: Drug Pricing
NOVEMBER 14, 2024
The company is paying China-based biotech LaNova Medicines $588 million for the type of dual-pronged antibody drug that recently bested Keytruda in a clinical trial.
PLOS: DNA Science
NOVEMBER 14, 2024
In 2019, I wrote about how sequencing the genomes of newborns might compromise their privacy if genetic information was not adequately protected as they grew up. Now five years later, researchers are recognizing a perhaps unexpected benefit of newborn DNA analysis – explaining seemingly unrelated symptoms in relatives. Newborn Screening for Metabolites, not DNA Screening newborns for telltale molecules other than DNA has been around for decades.
Practical Cheminformatics
NOVEMBER 16, 2024
Introduction Dataset splitting is one topic that doesn’t get enough attention when discussing machine learning (ML) in drug discovery. The data is typically divided into training and test sets when developing and evaluating an ML model. The model is trained on the training set, and its performance is assessed on the test set. If hyperparameter tuning is required, a validation set is also included.
thought leadership
NOVEMBER 7, 2024
Patient Support Programs (PSPs) in the pharmaceutical sector offer a range of services to help patients start and adhere to their therapies, including Patient Assistance Programs (PAPs), patient education, provider support, field role partnerships for injection and device training, concierge services for travel and lodging, and clinical trial support.
Science Daily: Pharmacology News
NOVEMBER 6, 2024
Older people who are sleepy during the day or lack enthusiasm for activities due to sleep issues may be more likely to develop a syndrome that can lead to dementia, according to a new study.
Drugs.com
NOVEMBER 15, 2024
FRIDAY, Nov. 15, 2024 -- An experimental vaccine has shown promise in protecting against the sexually transmitted disease chlamydia, researchers report.Lab mice given the vaccine were able to rapidly clear subsequent chlamydia infections, and were.
BioPharma Drive: Drug Pricing
NOVEMBER 14, 2024
A key regulatory committee sided against the drug this summer. But an appeal from Eisai appears to have worked, teeing Leqembi up for authorization in a major market.
Drug Patent Watch
NOVEMBER 12, 2024
Generic drug development is a crucial aspect of the pharmaceutical industry, providing cost-effective alternatives to brand-name medications. However, this process is not without its challenges. Here are the top 10 challenges faced by generic drug developers: Generic drug development involves navigating complex regulatory frameworks, including the U.S.
Drug Channels
NOVEMBER 13, 2024
Uh oh. As I predicted, the stand-alone Medicare Part D prescription drug plans (PDP) market is vanishing. For 2025, DCI’s exclusive analysis of Center for Medicare & Medicaid Services’ (CMS) data reveals that the number of PDPs will drop to a historic low. What’s more, the share of plans with a preferred cost sharing pharmacy network will fall to its lowest rate in more than 10 years.
thought leadership
NOVEMBER 7, 2024
Current Landscape of Medication and Healthcare Access in India India's healthcare system is a complex landscape with significant disparities in access to medical services and medications. Despite progress over the years, challenges such as high out-of-pocket costs, geographical disparities, and cultural barriers continue to affect healthcare accessibility, especially for economically vulnerable populations.
Science Daily: Pharmacology News
NOVEMBER 12, 2024
Roughly 90 million years ago, climatic conditions in Antarctica were suitable for resin-producing trees. Researchers have now made the southernmost discovery of amber in the world.
Drugs.com
NOVEMBER 7, 2024
THURSDAY, Nov. 7, 2024 -- More than a year after its advisory panel unanimously declared the drug phenylephrine to be useless against nasal congestion, the U.S. Food and Drug Administration is proposing that it be removed from common.
BioPharma Drive: Drug Pricing
NOVEMBER 13, 2024
Biotheus’ antibody drug targets PD-L1 and VEGF, a design that’s high on drugmakers’ radars after the success of Summit Therapeutics’ ivonescimab over Keytruda.
Drug Patent Watch
NOVEMBER 11, 2024
Effective management of drug patent portfolios is crucial for pharmaceutical companies to maintain market exclusivity, protect revenue streams, and drive innovation. A robust patent strategy aligned with business goals is essential for maximizing value and staying competitive in the pharmaceutical landscape.
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