Drugs.com

AUGUST 1, 2024

1, 2024 -- A next-generation nasal vaccine for COVID-19 appears to do what injectable vaccines can’t -- actually stop the spread of the virus from person to person.Hamsters that received the nasal vaccine didn’t pass the virus on to. THURSDAY, Aug.

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Drugs.com

OCTOBER 6, 2023

announced Wednesday that it has seen positive early results with a new vaccine that would guard against four strains of flu plus COVID-19. In interim findings from a Phase 1/2 trial, the vaccine showed both a. THURSDAY, Oct. 5, 2023 -- Moderna Inc.

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Vaccine Trials 278

Drugs.com

MAY 2, 2024

THURSDAY, May 2, 2024 -- An experimental cancer vaccine can quickly reprogram a person’s immune system to attack glioblastoma, the most aggressive and lethal form of brain cancer, a small, preliminary study has found.The cancer vaccine is based.

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Vaccine Trials 264

Science Daily: Pharmacology News

OCTOBER 17, 2024

A new vaccine provides hope for treating and even preventing the highly contagious and difficult-to-treat Clostridioides difficile infection, more commonly known as C. difficile vaccine was found to protect against C. difficile vaccine was found to protect against C. difficile or C. In animal models, this first mRNA-LNP C.

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Drugs.com

APRIL 8, 2024

MONDAY, April 8, 2024 -- A pancreatic cancer vaccine has continued to protect a small group of patients from their cancer coming back, three years after receiving the jab, a new study says.Eight patients have not had their pancreatic cancer recur.

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BioPharma Drive: Drug Pricing

OCTOBER 16, 2024

The hold, which was made in response to a serious adverse event report, could impact the company’s plans to start a Phase 3 trial of a combination shot for COVID-19 and influenza.

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Drugs.com

SEPTEMBER 4, 2024

4, 2024 -- Current vaccines against mpox were designed to fight an older, rarer cousin of the virus, smallpox.Now, new research from the drug company Moderna suggests its new mpox vaccine, based on mRNA technology, might do a. WEDNESDAY, Sept.

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Vaccine Trials Virus Research 246

Drugs.com

APRIL 9, 2024

TUESDAY, April 9, 2024 -- A custom-made anti-tumor vaccine added to standard immunotherapy was twice as likely to shrink liver cancer as when a patient received immunotherapy alone, a new study shows.The vaccine could help liver cancer patients.

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Vaccine Trials 246

BioPharma Drive: Drug Pricing

DECEMBER 5, 2023

The announcement ends a lengthy setback that began when the company and partner Valneva accused a clinical trial site operator of study misconduct.

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Trials Clinical Trials Vaccine 273

Science Daily: Pharmacology News

FEBRUARY 5, 2025

Researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney cancer), generated a successful anti-cancer immune response after initiation of a personalized cancer vaccine.

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Vaccine Immune Response Clinical Trials Trials 283

Drug Discovery Today

DECEMBER 22, 2020

First in human trials for vaccine candidate with the potential to confer long-term immunity

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Clinical Trials Vaccine Trials 192

Drugs.com

JANUARY 9, 2024

9, 2024 -- Patients with the most common form of pancreatic cancer could benefit from an experimental therapeutic vaccine, a small new clinical trial shows.The vaccine, called ELI-002 for now, is targeted to what are known as. TUESDAY, Jan.9,

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Vaccine Clinical Trials Trials 246

BioPharma Drive: Drug Pricing

JULY 8, 2024

Shares in HilleVax plummeted after the company reported its experimental shot failed to meet the primary and secondary goals of the Phase 2b study.

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Vaccine Trials 265

BioPharma Drive: Drug Pricing

MAY 10, 2024

The regulator cited “administrative constraints,” rather than any issue with Moderna’s trial data, for missing a May 12 deadline, the company said.

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Vaccine FDA Regulations Trials 265

Drugs.com

FEBRUARY 6, 2025

6, 2025 -- A small, early trial of a vaccine that mobilizes the immune system to battle advanced kidney cancers appears successful, researchers report.The "personalized cancer vaccines" (PCVs) used by the nine patients in the trial. THURSDAY, Feb.

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BioPharma Drive: Drug Pricing

AUGUST 16, 2024

The vaccine didn’t spur a strong enough immune response against a particular flu strain in a Phase 3 trial, leading the companies to ponder adjustments.

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Immune Response Vaccine Trials 294

BioPharma Drive: Drug Pricing

JUNE 10, 2024

Positive results from the trial could position Moderna to bring the two-in-one vaccine to market in 2025.

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PPD

JUNE 24, 2024

In the realm of vaccine development, mega trials — studies enrolling 5,000 subjects or more — have been instrumental in the fight against many pathogens, including influenza, rotavirus, malaria, RSV and most recently in the rapid development of vaccines against COVID-19.

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BioPharma Drive: Drug Pricing

APRIL 9, 2024

The company plans to submit the trial data to regulators in a bid to win approval of its vaccine Abrysvo in adults as young as 18 years old.

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Vaccine Regulations Trials 265

Fierce BioTech

FEBRUARY 26, 2025

Redefining vaccine trial recruitment Clinical trials are vital for developing safe and effective vaccines, but their success relies on overcoming recruitment challenges and ensuring diverse study cohorts. Discover innovative, data-driven recruitment strategies to ensure diverse, efficient, and high-quality vaccine trials.

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Vaccine Trials Clinical Trials Clinical Research 52

BioPharma Drive: Drug Pricing

JULY 26, 2023

The companies are enrolling people with melanoma in a Phase 3 trial aimed at testing whether the shot can prevent disease recurrence.

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Vaccine Trials Disease 246

BioPharma Drive: Drug Pricing

OCTOBER 4, 2023

The company is planning to start a Phase 3 trial of the vaccine this year, and is targeting a regulatory approval in 2025.

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Vaccine Trials 273

Codon

NOVEMBER 3, 2024

Even after microbiologists discovered the bacterium that causes the illness in 1882, it wasn’t until the 1920s that researchers were able to develop a vaccine for TB. These breakthroughs have significantly curbed cases, with vaccination reducing the odds of death by 74 percent. tuberculosis , to develop the vaccine.

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Vaccine Trials Therapies Treatment 98

BioPharma Drive: Drug Pricing

JULY 27, 2023

The pharma said its latest shot, which covers 21 strains of bacteria, cleared two Phase 3 trials and in some cases spurred a stronger immune response than Pfizer’s Prevnar 20.

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Immune Response Vaccine Trials 245

BioPharma Drive: Drug Pricing

OCTOBER 26, 2023

The partners announced the trial had succeeded weeks after Moderna disclosed positive results from a study of its similar combination vaccine.

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Drug Discovery Today

APRIL 15, 2021

First subjects dosed with AKS-452, COVID-19 vaccine candidate in the Netherlands trial the vaccine is shelf-stable for 4 months at 25 degrees Celsius (77° Fahrenheit). 176 volunteers will participate in the clinical trial the safety and immune response read-outs expected in Q2 2021

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Clinical Trials Vaccine Trials Immune Response 113

BioPharma Drive: Drug Pricing

JUNE 13, 2024

Trial data suggest the shot — an important component of an upcoming combination inoculation — has proven at least as effective, and in some cases superior, to the company’s initial COVID vaccine.

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Vaccine Trials 209

BioPharma Drive: Drug Pricing

SEPTEMBER 3, 2024

The company's value jumped by several billion dollars as trial results showed its experimental shot could match and, in some cases, even outperform Pfizer's market-leading Prevnar 20.

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Vaccine Trials Marketing 164

BioPharma Drive: Drug Pricing

APRIL 2, 2024

While the company claimed its shot showed signs of working in a Phase 2 trial, the data weren’t strong enough to prove a treatment benefit.

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Vaccine Trials Treatment 164

SCIENMAG: Medicine & Health

AUGUST 3, 2023

The Access to Advanced Health Institute Receives $18 Million Award to Develop a Temperature Stable, Single-Dose Chikungunya RNA Vaccine Through a Phase 1 Clinical Trial Credit: Delaney Brown Photography The Access to Advanced Health Institute Receives $18 Million Award to Develop a Temperature Stable, Single-Dose Chikungunya RNA Vaccine Through a Phase (..)

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RNA Clinical Trials Vaccine Trials 93

Drug Discovery Today

JANUARY 22, 2020

A new analysis of the clinical trials of HPV vaccines to prevent cervical cancer raises doubts about the vaccines’ effectiveness. The analysis, published by the Journal of the Royal Society of Medicine, assessed 12 published Phase 2 and 3 randomised controlled efficacy trials of the HPV vaccines Cervarix and Gardasil.

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BioPharma Drive: Drug Pricing

OCTOBER 7, 2024

The development of cancer vaccines has provided some hope in the battle against cancer worldwide; however, there are still many challenges to overcome when developing these life-saving treatments.

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Disease Trials Vaccine Treatment 130

BioPharma Drive: Drug Pricing

OCTOBER 12, 2023

Earlier this year Pfizer removed thousands of participants from a study of its Lyme disease shot over concerns the group, Care Access, wasn't meeting clinical practice standards.

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Vaccine Trials Research FDA 156

DrugBaron

JANUARY 2, 2021

Over the past week a furious debate has broken out over the merits of delaying the second dose of the approved COVID vaccines, to increase the number of people who can be given a single dose. The case against doing so is clear: the labels of the approved vaccines are unambiguous that two doses should be given within a certain time window.

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PPD

JULY 6, 2023

It’s estimated that nearly three out of every four clinical trials are conducted by contract research organizations (CROs), highlighting just how much sponsors value — and rely on — the work that CROs perform. Surveys show that CROs improve trial efficiency and increase productivity.

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Clinical Trials Trials Drug Development Testimonials 98

The Pharma Data

AUGUST 27, 2020

Moderna has announced that its coronavirus vaccine candidate has shown promise in generating an immune response in elderly patients in an early-stage clinical trial. . Each patient was given two 100 microgram doses of the vaccine 28 days apart. There is hope that Moderna’s vaccine could be available by early 2021. .

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DrugBank

JULY 18, 2024

Vaccines have consistently demonstrated their efficacy in protecting people from infectious diseases. Yet, the recent COVID-19 pandemic highlighted the obstacles that are inherent today in the development of vaccines. Stabilizers play a crucial role in maintaining the vaccine's potency and integrity throughout its shelf life.

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